Cladistic methodology is discussed in the context of mosquito chromosome inversions, and the available data within Anopheles subgenus Cellia is reinterpreted. Within the Myzomyia Series, a sister group relationship is corroborated between the Wellcomei Group and the clade Funestus Group + Rivulorum Group, leaving the Demeilloni Group as a clade of uncertain position. Within the Neocellia Series, only two groups are recognized as monophyletic: the Maculatus Complex and a clade consisting of An. rufipes + An. maculipalpis + An. pretoriensis. For the Gambiae Complex of the Pyretophorus Series, the sister group relationships An. bwambae + An. melas and An. gambiae + An. merus are confirmed, although outgroup data is almost absent, making hypotheses highly premature.