5 ri 
Refpedin 
fufficiently agr 
the 
S 
al appli 
2 alledg 
c 
th 
of opium authors fcem not 
ays pam 
d fpafi 
pplied to the fk 
pr 
or 
dangerous effects which refult ft 
ileep, and produces all th 
d 
ufe : 
hile othe 
ary 
aflert that, thus applied, it has little or no efFed whatever. But there is 
doubt that, when mixed with cauftic, it diminifhes the pain, which 
would other wife enfue, probably by decreail 
th 
part 
a 
Injeded up the redum, it has all the e 
the ftomach, but to anfwer this purpofe double the q 
ployed. Applied to the naked nerves of 
•ility of the 
opium taken 
immediate torpor, and lofs- of no 
pro 
all the 
hich 
mmunicate. Opium taken into the flomach 
oderate dofe, proves a narcoti 
mvulfions, delirium, ftupor, ft 
poifon, pro 
vertigo, tremors, 
Th 
officinal preparat 
of th 
d finally fatal apoplexy 
dr 
pilulse ex opio, pulvis opiatus, tindura op 
g are opium purifi 
ii. and " : -^ 
tmciura opn cam 
pi 
it alfo enters the pul 
fi 
ficus, balfamum anody 
eleduarium japonicum, pulvis e creta compoiita, &c. 
The requifite dofe of opium varies in different perfons, and in 
different ftates of the fame perfon. A quarter of a grain will in one 
adult produce effeds which ten times the quantity will not do in 
anothe 
would 
and 
dole th 
perceptibl 
might 
many 
prove 
fatal 
m 
hoi 
or 
ic 
? 
fes of 
or mama. 
The 
lowed fatal dofe, to thofe unaccuitomed * to take it, feems to be about 
four grains; but a dangerous dofe is fo apt to produce vomiting, that it 
has feldom time to oCcafion death. When given in too fmall a dofe, 
it often produces difturbed lleep, andother difagreeable coniequences; 
and in fome cafes it feems impoffible to be made to agree in any dofe 
Often, on the other hand, from a fmall dofe, found lleep and 
fo 
rm 
alleviation of pain- will be produced, while 
g 
one 
vertigo and del 
S 
others the g 
it eight 
prefer the rep 
fi 
of fmall dofe 
abo 
o 
full dofe at once; its operation is fuppofed to laft 
It 
d 
creafed to produce the effect delired ; and we 
ires to be ln-r 
which it was . 
drams a day 
Garcia i ' Ab HvrtQ A\ 
a us. 
/ 
N 
o. 
•5b ." 
PA PA V E R, 
