553 
order in which they are placed: Dulcified fpirit of vitriol: Caufti< 
French brandy: Rhenifh wine : Soft water: Vinegar and wa 
ter : Dulcified fpirit of nitre : Mild volatile alkali : Redified fp„__ 
f wine : Mild vegetable alkali : Lime-water. The antifceptic powers 
of vinegar and bark united are double their film taken ieparately. 
The aftringent power of the bark is increafed by acid of vitriol ; 
the bitter tafte is destroyed by it. 
Though the bark on its firft introduction, and even fome time 
afterwards, was reprobated by fome eminent phyficians as a dan- 
gerous remedy; yet thefe prejudices are entirely done away, and its 
character is now univerfally eftablifhed: fo that the difputes which at 
prefent fubfift are confined to its mode of operation, or the manner 
in which it is moft efficacioufly adminiftered. To detail thefe, 
however, or even to give a circumflantial relation of the various 
Hates of difeafe in which the bark might be advantageoufly em- 
ployed, would far exceed our limits : we are therefore confined to 
ftate briefly thofe difeafes to which this medicine is more efpecially 
adapted. 
The bark firft acquired its reputation for the cure of intermittent 
fevers, and in thefe, when properly exhibited, it rarely fails of fuccefs* 
For this purpofe, fome practitioners prefer giving it j uft before the 
fit, fome during the fit, and others immediately after. Dr. Cullen, who 
is of the firft opinion, fays, " I am fatisfied that giving a large dofe 
of the bark immediately before the time of acceffion, is the moft proper 
pradice : but as that dofe muft not be under two drams of pale bark, 
there are fome ftomachs which will not bear even that quantity 
or a larger that might be neceffary. It is commonly, therefore, 
convenient to give fmall dofes, but to give them every hour for fome 
hours near to the times of acceffion." 8 Some again order it in the 
quantity of an ounce between the fits ; the dofe being more frequent 
and larger, according to the frequency of the fits ; and this mode of 
procedure, although it may perhaps lead to the employment of more 
bark than is neceffary, is confidered by Dn Duncan as upon the 
preferable, from being beft fuited to moft ftomachs. When 
X 
Mat. Med. Vol p. 97. b See Nm Edinburgh Diftmfatory 
the 
