86 
and the writer. During the investigation of the pathologic anatomy of 
that disease I discovered the presence of the ova which, in the opinion of 
Shiga, Fujinami, and Stiles, are those of S. japonicum v. cattot. 
The autopsy was performed by Dr. Musgrave a few minutes after the 
death of the patient. ‘There was an old, discharging abscess on the right 
arm and another on the right side of the thorax extending into the 
pectoral muscles. The subcutaneous fat was well preserved and the 
muscles were somewhat pale. The left lung showed an intense conges- 
tion, with cedema of the lower lobe. The right was also congested and 
an abscess, over which the two layers of the pleura were firmly adherent, 
was present in the lower lobe, binding the lung to the diaphragm, ribs, 
and sternum. The cavity of this abscess, resembling those seen in 
ameebiasis, was filled with a thick pus. The abdominal cavity was free 
from adhesions. ‘he walls of the intestine were somewhat thickened and 
the mesenteric lymphatics moderately enlarged. The spleen was enlarged 
and a well-marked chronic perisplenitis was present; it was adherent to 
the diaphragm, and its surface was wrinkled and pale. The liver showed 
a considerable perihepatitis and was bound to the diaphragm and abdom- 
inal wall by firm adhesions. On the dome was a large scar resembling 
that resulting from a healed abscess; about this were old and dense 
adhesions. On section, the liver was pale and cloudy, giving an increased 
resistance when cut. The kidneys showed a moderate parenchymatous 
degeneration. The stomach and the small intestine showed a well- 
marked catarrhal condition, and in the former there were a few small 
hemorrhages. In the upper 40 centimeters of the small intestine there 
were a number of uncinaria. The large bowel gave evidence of amoebic 
infection throughout, but the most marked pathologic changes were in the 
transverse and descending colon, and less in the caecum and rectum. In 
the most advanced lesions the process simulated a hemorrhagic enteritis 
in which small superficial ulcerations predominated. These ulcerations 
displayed a considerable variety, but the deep-sloughing, undermined 
ulcer was not present. The appendix was not involved. (Musgrave.) 
Microscopically, large numbers of amcebw were found in scrapings from 
the ulcers and in the intestinal contents, but none could be demonstrated 
in the pulmonary abscess. Ova of uncinaria were also present in the 
intestinal contents. 
Tissues from the intestine, liver, and lungs were secured and_pre- 
served in Kaiserling’s solution. Bits of these were embedded in celloidin 
and paraffin. Sections were stained with hematoxylin and eosin. 
The histological study showed that the mucous membrane of the large 
intestine was atrophied and, in areas, eroded. The submucosa was thick- 
ened and edematous. The muscular layers presented but little change. 
The ova occurred chiefly in fibroid tissue in the submucosa, where they 
were innumerable and surrounded by round-celled infiltration. In the 
