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passed in the stools. Whether infection occurs through the skin or not is 
still a question, though from the distribution of the eggs in the body we 
would suppose that it occurred by the gastro-intestinal route. However, 
the same is true of uncinariasis, and still there appears to be considerable 
evidence of the occurrence of the latter infection through the skin. 
The significance of this new case is evident. It means that not only 
in China and Japan but also in the Philippines there is a disease caused 
by a blood parasite which may of itself, or by its eggs, and perhaps also 
by a toxin, produce a serious condition resulting in cirrhosis of the liver, 
splenomegaly, ascites, dysentery, progressive anzemia, and also, possibly, 
epilepsy of the Jacksonian type. In certain stages of the infection the 
condition may be confused with tropical splenomegaly, of which it 
possibly is one of the much-sought-for causes; or with amoebic dysentery 
or uncinariasis, with either or both of which it may be combined, or with 
epilepsy. It is very probable, now that a case has been encountered, 
that further ones will be discovered, and perhaps it will be found to be 
nearly as common, both in China and the Philippines, as it is in Japan. 
The following method of staining the ova in the tissue was devised by 
Mr. Willyoung, of the Biological Laboratory : 
Celloidin sections were immersed in water and then stained in a solu- 
tion containing 1 per cent acid fuchsin and 2 per cent oxalic acid. ‘They 
were then washed in water and stained in an aqueous solution containing 
0.12 per cent of aniline blue and 1.2 per cent oxalic acid. Differentiation 
was accomplished by using acid aleohol and 80 per cent alcohol. By this 
means the ova were stained a brilliant red and the tissue a clear blue. 
SUMMARY. 
In lesions in the lungs, liver, and the bowel of a Filipino, ova have 
been found which agree in shape, size, and color with those of Schis- 
losoma japonicum vel cattoi. 
The lesions in the bowel were ulcerations closely resembling those seen 
in some forms of amebiasis; those in the liver were characterized by 
fibrosis. 
The symptoms were not definite, because of the mixed infection with 
other intestinal parasites. 
From these observations it follows that in China, Japan, and in the 
Philippine Islands there is a trematode worm differing characteristically 
in its morphology from the allied African species, which produces lesions, 
especially in the large intestine and liver, and which has been described 
as Schistosoma japanicum vel cattoi. ‘The case under observation is, to 
the best of my knowledge, the first schistosoma infection encountered in 
the Philippine Islands, and, therefore, now that it has been called to the 
attention of investigators, it seems not unlikely that other cases will be 
discovered. 
