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these bodies were partly inclosed in epithelioid cells, the nuclei of which some- 
times appeared to be pushed to one side. In other places, where they apparently 
were not enveloped in cells, the bodies lay in groups in such a manner that one 
might believe that they were lying inclosed in the same envelope, but that 
optically the latter could not be distinguished. The bodies themselves existed, 
first, as a deeply stained round or more elongated chromatin granule; and 
secondly, one about double the size, seldom three times as large, and of a some- 
what different appearance. This second body probably representated a proto- 
plasmie form, which in the central portion was lightly stained and at the margins 
was more deeply colored, so that sometimes a ring form resulted, at the periphery 
of which the deeply stained round body was situated. In a favorable light not 
infrequently there could be seen a second, very small, deeply stained round or more 
elongated granule, which either was attached to the larger one or which also 
appeared in the periphery of the ring, opposite to the larger body. The entire 
form sometimes seemed to be inclosed in a round or oval halo, which was either 
stained or remained uncolored. 
Plehn remarks that, as the description demonstrates, the similarity of these 
forms to Leishman’s bodies is very great; at any rate, we have to do with the 
occurrence of protozoa in Oriental boil, and the peculiar nature of these organisms 
makes it probable that they are the specific cause of the disease. 
James (3) (1905) has very recently examined 18 cases of “Delhi sores” and 
found, in all of these, peculiar bodies which he believes to be parasites. The 
bodies were found within large endothelioid cells and under a low power appeared 
as microcoeci in the protoplasm of the cell. A large number were also scattered 
through the films or sections, which were not inclosed in cells. When examined 
under a high power, these bodies, which resembled micrococci, possessed a very 
definite appearance and structure. Most of them were then seen to be oval in 
shape, but slightly broader at one end than at the other. However, a good many 
were quite round and some were pointed at both ends. The bodies varied con- 
siderably in size, but the length of the majority was about one-half the diameter 
of a red corpuscle. ‘Their circumferences were remarkably regular and distinct, 
as if they were provided with a definite capsule. The greater portion of their 
substance stained a light blue, but near the center there was a large unstained 
area, sometimes divided into two by a streak of blue-stained body substance. 
In the interior of each body two masses of chromatin were seen. One of these 
was large in size, more or less rounded in shape, and was usually situated 
near the center, but always touching one edge of the circumference. The 
second chromatin mass varied in shape from a dot to a comparatively long, 
thick rod. In the latter case it usually lay near the center and at right angles 
to the long axis of the parasite. It stained more deeply than the large chromatin 
mass. In some parasites James saw a third, rod-shaped mass of chromatin, 
usually situated near the more-pointed end of the former and at right angles 
to the second. This was present in only a few of the bodies in each film. 
On the other hand, several competent observers, who have carefully 
examined specimens supposedly of this disease, have encountered no 
specific parasites. 
Thus Unna, (12) (1894) who made a very careful histological examination of a 
specimen of Delhi boil sent from Constantinople by During, was unable to find any 
bacteria or other parasitic organisms in his sections. In a section from Riehl’s 
ease he found micrococei in enormous numbers within the necrotic cell masses, but 
they were not intracellular as Riehl had described them to be, all of those which 
Unna could distinguish being intercellular. Leloir (11) after diligent search was 
