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Seven days. Nose: Mucous membrane swollen and presents an opaque, white 
elevation on the septum. Lip: Lesion is 1 centimeter in diameter, border slightly 
irregular and overhanging in places, central portion depressed and eroded, 
showing in places red granulation tissue and in places islands of macerated epi- 
thelium. The mucous membrane about the lesion is hyperemic. Palate: An 
opaque, gray area, 10 X 4 millimeters, edge elevated and surrounded by an areola. 
Body temperature 39°.5 C. 
Eight days. Nose: Yellow crusts are visible, but swelling of the mucous mem- 
brane renders close inspection impossible. Lip: Lesion is the same as yesterday 
save that the areola has faded. Palate: Same as before save that areola is 
absent and the lesion has not extended. Body temperature 39° C. Animal chloro- 
formed and autopsy done at once. Lesions at site of inoculation as described 
above; internal organs show no evidence of specific lesions. 
No. 83, Adult male M. cynomoloqus. Inoculated on the septum of the nose, 
inside of the lip and on the soft palate with vaccine virus No. 1. Body tem- 
perature 39°.8 C. 
Twenty-four hours after the inoculation no specific lesion is macroscopically 
evident. Body temperature 39°.6 C. 
Forty-eight hours. Nose: A narrow red crust is evident. Lip: Palate shows 
no reaction. Body temperature 38°.8 C. Animal chloroformed and autopsy done 
at once. Extensive lesions of tuberculosis were present. This case will be de- 
scribed from the point of view of the intercurrent disease in another article. 
No, 84. Adult male M. cynomologus. Inoculated in the nose, on the lip and 
palate with vaccine virus No. 1. Body temperature 39°.5 C. 
Twenty-four hours after the inoculation no evidence of reaction is visible. 
Body temperature 39°.2 C. 
Forty-eight hours. Nose: Negative. Lip: Small, red, papular elevation on line 
of inoculation. Palate: Red line marks site of scratch. Body temperature 38° C. 
Three days. Nose: A small gray crust is visible on the septum. Lip: 2 
opaque, white elevations, 2 millimeters in diameter, are present, one at either end 
of the line of inoculation. Between these white spots runs a narrow white line. 
There is considerable reddening of the mucous membrane about the lesion. Palate: 
2 small, opaque, white elevations, 1.5 millimeters in diameter, are joined by a 
narrow red line. Body temperature 39° C. Animal chloroformed and an autopsy 
done at once. Lesions at the site of inoculation as described above. The mucous 
membrane of the respiratory and digestive tracts examined and no evidence of a 
vaccine lesion found. ; 
No. 85. Adult male M. cynomologus. Inoculated on the inner surface of the lip, 
on the nasal septum, and on the soft palate with vaccine virus No. 1. Body tem- 
perature 38°.8 C. 
Twenty-four hours after the inoculation there is slight redness about the incision 
on the lip. The nose and the palate are negative. Body temperature 39° C. 
Forty-eight hours. Nose: A brown crust is visible. Lip: The redness persists. 
Palate: 2 small yellow papular elevations are seen on the line of the inoculation. 
Body temperature 39° C, P 
Three days. Nose: Crust is still present. Lip: A small, opaque, white area, 
1 X 2 millimeters, seated upon reddened mucous membrane. Palate: 2 opaque, 
white papular elevations, 2 millimeters in diameter, and elevated 1 millimeter 
above the general surface, surrounded by a pink flush. Body temperature 39°.2 C. 
Four days. Nose: Small vesicle with a pink, peripheral flush. Lip: Opaque, 
