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for the whiteness of recently healed varicella lesions in Filipinos. The 
vesicle may persist as such until the surface beneath is completely healed, 
or it may be ruptured and form a thin crust on drying. 
In the corium, the migrating cells gradually become reduced in num- 
bers, the infiltration about the blood vessels is diminished, and with the 
repair of the defect in the epidermis the underlying tissue also returns 
to its normal state. 
In addition to the typical lesions upon which the description of the. 
process has been based, certain other atypical lesions occur. 
Vesicle within vesicle—In a certain percentage of the lesions there is 
a secondary extension of the lesion. After the vesicle is apparently well 
developed, it still remains tense and when seen on the following day, an 
increase in size is noted and the outline of the former vesicle is seen within 
the large lesion. The original vesicle is clouded and opaque, while the 
newly formed one is clear. This condition is brought about by the 
leakage of fluid from the cavity of the original vesicle, into the horny 
layer which it splits. (PI. ITI, fig. 15.) It seems probable that the 
larger blebs and bullew sometimes met with in these cases are formed in 
this way, as they appear to be very superficial. 
Dry or abortwe lesions——In a small number of lesions there appears 
a marked localized degeneration of the epithelial cells unaccompanied by 
any appreciable exudation. These lesions appearing as reddened, slightly 
elevated spots in the gross show microscopically a portion of the epidermis 
wholly necrotic, the cells of which are disassociated, stain red, and are 
hyaline in appearance like those in the advance vesicle. Reticulating 
colliquation is not represented. Such lesions are simply lacking in fluid 
exudate. (Pl. IIT, fig. 16.) ‘'Fhis condition is difficult to explain, 
especially when cases occur in which a majority of the lesions develop 
in this way. A case illustrating this condition is as follows: 
Case No. 28, June 8, 1904.—A Filipino, young adult, having two old vaccination 
sears. The eruption has appeared within the last twenty-four hours, and is 
seanty. It is papular on the face and mixed with acne. Several clear vesicles, 
5-6 millimeters in diameter in groin, few papules on legs. A vesicle 5 mil- 
limeters on anterior thorax, one 2 millimeters back of the shoulder, and a few 
small vesicles on arms and forearms. 
June 9, 1904.—Eruption has increased and is seattered over the entire body. 
It consists of small reddened spots, the majority of which have a slightly 
elevated granular surface. None on hands or wrists. Face, rough and papular. 
Mouth negative. 
June 10, 1904.—The eruption is now profuse and simulates an early smallpox 
eruption. It consists of small red papules two to four millimeters across, with 
granular tops. Some papules have at their summit a tiny vesicle in the center 
of a slightly roughened surface. A few clear, hemispherical vesicles have devel- 
oped. Lesions are profuse on face and trunk, scattered over arms and legs, none 
on palms. 
June 11, 1904.—Very few papules have become vesicular. Many lesions have 
faded out and practically disappeared. Following this date no new vesicles 
appeared and those present healed rapidly. 
