Ss. Sawa Se. Oe 
466 
spread to Osaka, where its ravages reached a high mark, and then invaded 
Hamamatsu and Wakayama. The total cases in this epidemic num- 
bered 230. 
The second invasion was in 1902 and 1903, the source of this epidemic 
probably being in cotton which was imported from Hongkong. The 
initial cases occurred in Yokohama and it then spread to a district in 
Tokyo. The epidemic was stopped by the combined efforts of the two 
cities after it had claimed 71 victims. 
The third outbreak occurred in 1905 and is still prevailing. | 
out different localities—namely, in Tokyo, Chiba, Kobe, Osaka, Kagawa, 
and Moji—a number of victims have succumbed to it. ‘The disease ap- 
peared in Tokyo in the early spring, chiefly in the Fukagawa district, 
and it then spread to the Chiba perfecture, where a summer epidemic 
prevailed to a slight degree. The origin of the outbreak in Kagawa, 
lasting from May to the middle of June, appears to have been similar 
to that of the Osaka and Kobe epidemic and it was evidently due to 
direct contagion ; its severity has been unparalleled in recent years. ‘T'wo 
plague patients were found in the city of Kobe in August and the number 
of cases increased rapidly within the next few months, so that during the 
year the total number of victims amounted to 90. Next to Kobe, Osaka 
suffered most severely, there having been many cases since October of 
the past year, the number reaching 134 in three months. In both cities 
the outbreak spread throughout all the districts and it is still raging. 
Plague has also appeared in Shimonoseki and has claimed nine victims 
in that city. This epidemic has had no precedent both in its severity 
and in the number of its victims, the total of the cases during the year 
having reached 297. 
The following table shows the regions of Japan in which the series of 
outbreaks occurred and the number of patients in each: 
Year. | Patients. | Deaths. | Principal regions of the inane! 
| 
1899 62 45 | Kobe and Osaka. 
Wivet outbreak ....:......-...-.. 1900 168 153 | Kobe, Osaka, Hamamatsu, | 
Wakayama, and Nagasaki. | 
1901 2 2 |) Wakayama. 
‘Sivek onthe... { 1902 14 9 | Yokohama and Tokyo, 
1903 57 49 | Do. 
Thin OnthreaKes..a....2.-=. .-.- { 1904 1 1 | Kobe. | 
1905 297 257. Tokyo, Kobe, Osaka, Chiba, Ka- | 
gawa, Moji,and Nara. 
acme Ae, See 601 513 
The number of patients during the past year, distributed in different 7 
localities, is as follows: 
Tokyo, 15; Chiba, 11; Osaka, 134; Nara, 2; Kagawa, 36; Kobe, 90; 
Moji, 9; total, 297. 
