604 The Philippine Journal of Science 1922 
ending, or at the hypothetical myoneural junction.(5,12) We 
applied the drug on the fiber of the short ciliary nerve, but 
we have not succeeded in limiting it there. However, since 
in general the nerve endings are more susceptible to the action 
of drugs than are the nerve fibers, it is highly probable that 
Datura alba caused mydriasis by paralyzing the ending or the 
myoneural junction of the oculomotor nerve. 
ACTION ON THE SALIVARY GLANDS 
We used dogs in our experiments on the salivary glands. 
The animals were anesthetized with morphine and chloretone. 
One femoral vein was connected with an injection burette. 
The chorda tympani and the salivary gland of one side were 
isolated and protected from exposure. The flow of saliva was 
recorded by a drop-recorder. Table 4 is an abbreviated pro- 
tocol of one of our experiments. 
TABLE 4,—Action of Datura alba on the submawzillary gland. 
[Date of experiment, January 12, 1921.] 
. Amount 
Time. Procedure. winner" Remarks. 
minute. 
p.m.| . Drops. 
2.40 | Stimulation of chorda tympani-____.--.-...---.------ 6 | Saliva ceased after a few 
drops. 
2.42 | Stimulation of gland _____-___ sees 4 Do. 
2.50 | 2 decimils of 1 per cent pilocarpine were injected |........-.|--------.--------------------- 
to increase flow of saliva. : 
ee re re 8 | Salivadropped continuously 
and tended to increase. 
8.08 | 4 centimils of the preparation injected__-_......--__- 0 | Saliva flow ceased 30 sec- 
: onds after injection. 
Wea L emulation ofaland 0 oo ec ce cb boa ak 4 | 1 drop per 3 minutes. 
3.15 | Stimulation of chorda tympani____........---.------ 0 
O21 | Stichulation of Mand |... 5 4 | 1 drop per 2 minutes. 
3,24 | 4 decimils of 1 per cent pilocarpine were injected___ 0 
3.27 | 5 decimils of 1 per cent pilocarpine were injected___ 4 | 1 drop per 3 minutes. 
4.06 | Simulation of gland = 4 | 1 drop per 2 minutes. 
EON teak ye ee ee, 1 
8.40") Stimulation ofwland =o. ir 2 
3.45 | Stimulation of chorda tympani__.......____ ______ 1 | No change in the rate of 
flow. 
8.48 | 5 decimils of 1 per cent pilocarpine were injected__. 2 
3.55 | Stimulation of chorda tympani___.._............... 4 
eaeeder — 
Table 4 shows that 4 centimils of aqueous preparation of 
Datura alba seed easily overcome the action of 2 decimils of 
