20, € Schwartz: Ascaris vitolorum 667 
larvee, by Ransom and Cram,(2) the following statement with 
reference to the sojourn of larve in the liver occurs: 
After the fifth day they are usually so scarce as to be found with difficulty 
and often none are found even after repeated examination. In the present 
series of experiments no larvae were found in the liver later than seven 
days after infection. 
Ransom and Cram examined the livers of sixty-eight animals, 
- of which fourteen were examined later than seven days after 
feeding the eggs. In five cases in which the duration of 
infection was seven days, only one liver was positive, the infec- 
tion being light. In fourteen cases in which the duration 
of the infection was from eight to twelve days, the livers 
were all negative. I have found the liver of guinea pigs heav- 
ily infested with larve five days after artificial infection, 
whereas Ransom and Cram found larve in the liver of four 
out of five guinea pigs during a similar stage of infection, 
but the larvze were not numerous. I have found numerous 
larvee in the liver of guinea pigs nine days after feeding eggs, 
and in one case I found the liver heavily parasitized by larve 
thirteen days after feeding eggs. In the last case numerous 
press preparations of the lungs were made, but no larve were 
found despite the fact that these organs still showed numerous 
petechial hemorrhages characterestic of Ascaris pneumonia. 
Guinea pigs examined nine days after feeding eggs usually 
contained more larve in the liver than in the lungs, so far as 
could be judged by the relative abundance of the parasites in 
these organs as seen in press preparations. 
It appears evident, therefore, that the larve of Ascaris vito- 
lorum sojourn in the liver of guinea pigs for a relatively long 
time. The fact that they are still abundant in the liver after 
the lungs have become free from them indicates that larve of 
A. vitolorum are arrested in the liver in heavy experimental 
infections, and that many of these larve probably fail to reach 
the lungs. Further studies on this phase of bovine ascariasis 
in experimental animals are in progress. 
In heavy experimental infections larvee were also found in 
the spleen, pancreas, kidneys, and heart cavity nine days after 
infection. The kidneys were heavily infested, and larve were 
found in the cortical as well as in the medullary portions. The 
presence of larve of Ascaris lumbricoides in the kidneys was 
overlooked in the earlier studies on the migrations of the 
larve. Yoshida(4) and Filleborn(1) found them in these organs. 
