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Suprarenals: vessels highly congested, cells of the zona fascicularis highly vacuo- 
lated. Liver: the parenchyma cells show a moderate degree of fatty infiltration 
and degeneration, The interlobular connective tissue exhibits acute, inflammatory 
foci, composed of small, round cells. Spleen normal, pulp spaces densely filled 
with blood. Here and there one sees a pigmented malarial parasite; eosinophilic 
cells are very numerous throughout the sections. In the stomach, the duodenum 
and also in the large intestine the vessels of the mucosa are highly congested and 
the eosinophiles increased, but otherwise the organs are normal. The eosino- 
philic cells are found in largest numbers in the lower strata of the mucosa, next 
to the muscularis mucosa. Here are often seen from 30 to 60 eosinophilic 
leucocytes in one field, one-twelfth oil immersion, ocular No. 3; length of tube, 
170 millimeters. The pancreas is normal. The tonsils are norma! but in the 
recesses of the crypts there are found a large number of bacilli greatly resembling 
those of diphtheria. Sections from both the crural and the popliteal nerves show 
profound degenerative changes. The latter nerve is more markedly affected. 
Few intact myelin sheaths are visible. The remaining ones are nodular, beaded, 
fragmented, and in a state of complete, foamy or honeycombed degeneration. The 
axis cvlinders are frequently irregular, shriveled, more or less twisted, or entirely 
absent. The neurolemma nuclei are moderately increased. Inflammatory changes 
are not present. 
Case No. 2.—Acute pernicious beriberi.—Necropsy No. 1595, January 3, 1906: 
Jorge Madulid, 33 years old, a Filipino prisoner in Bilibid, suffered slight malaise 
for several days before his admission to the hospital at about 4 o’clock on the 
afternoon of January 2, 1906. At this time he was very ill, suffering with rest- 
lessness, shortness of breath, palpitation of the heart, and rapid and weak pulse. 
His symptoms increased in severity and he died at 9.45 p. m. 
Autopsy January 3, 1906, fourteen hours after death: Body of a strong, well- 
nourished male Filipino about 30 to 40 years old. The skin at the dorsum of the 
feet and at the anterior surfaces over the tibiwe is slightly cdematous. Rigor 
mortis moderate, On section the superficial veins discharge a considerable amount 
of dark, fluid blood. The subcutaneous tissues are moderately cedematous, the 
muscles pale-pink and moderately moist. The abdominal cavity contains about 
50 to 100 cubic centimeters of a clear, straw-colored fluid. The pericardium is 
considerably distended and contains 100 to 150 cubic centimeters of a liquid of 
the same color. The heart is enlarged, particularly the right ventricle. Here 
the myocardium measures from one-half to three-fourths of a centimeter in 
thickness. Both sides of the heart contain much dark, fluid blood besides chicken- 
fat clots. The auriculo-ventricular opening of the right side is considerably 
enlarged and easily admits four fingers. Both the pericardium and endocardium 
are smooth and the former shows a few, very small petechie. The myocardium 
as a whole is rather soft and flabby and of a pale-pink and grayish-yellow color. 
The heart weighs 340 grams. The lungs are heavy, the pleure smooth and trans- 
parent, showing quite a number of petechiz and ecchymoses. On section, the 
lungs are dark, reddish-brown in color, highly congested, and very poor in air. 
The mucosa of the larynx, trachea and bronchi is somewhat swollen, hyperemic 
and covered with a thin, foamy, slightly blood-tinged mucus. The spleen is con- 
siderably enlarged. The capsule is of a dull gray color, quite opaque, and here 
and there shows circumscribed areas of peri-splenetic thickening. The resistance 
of the organ is increased. On section, it is found to be dark, reddish-brown in 
color and very much congested. The trabecule are very distinct and quite notice- 
ably widened. The pulp is highly congested. The kidneys are normal in size, 
grayish-pink in color on the surfaé@es and dull and somewhat grayish-vellow on 
the cut surface. Ureters, bladder, ete., are normal. The liver is somewhat swol- 
len, its margins rounded, capsule smooth, transparent and dark, purplish-brown 
