i 
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974 
sera, prepared with so-called non-fermenting bacilli, often agglutinate 
strains which ferment mannite in the same or in higher dilutions than 
they do other organisms of the non-fermenting type, and vice versa. The 
same phenomena can also be confirmed by bacteriolytic tests, the so- 
called “cross bacteriolysis” usually taking place between bacilli termed 
both acid and non-acid. 
(4) In consideration of all the above facts it seems to me that no 
reason exists to separate the dysentery bacilli into two distinct groups, 
the acid and non-acid, as proposed by Lentz, and I can also see no jus- 
tification in designating any bacillus which causes dysentery as a “pseudo- 
dysentery bacillus” according to Kruse. We are compelled to consider 
the fifteen types of dysentery bacilli as constituting a single group. 
Finally, I take great pleasure in acknowledging my indebtedness to 
Professor Kitasato, director of the Government Institute for Infectious 
Diseases in Tokyo, for many suggestions and kindnesses; I am also under 
obligations to Dr. Shiga for important suggestions and kind assistance. 
I desire also to express my obligations to Dr. Strong, director of the 
Biological Laboratory, Bureau of Science, Manila; Dr. Momose and 
Dr. Hirano, naval fleet surgeons of the Imperial Japanese Navy, and 
Dr. Hata and Dr. Oshida, military lieutenant surgeons of the Imperial 
Japanese Army for courtesies shown by them in sending me materials 
for this study. My thanks are also due to Dr. Hidaka for assistance in 
my experiments. 
REFERENCES. 
(1) Flexner: On the Etiology of Tropical Dysentery. Phila, Med. Journ. 
(1900), VI, 414. Also Bull. Johns Hopkins Hosp. (1900), XI, 231. 
(2) Strong: Ibid. Phila. Med. Journ. (1900), VI, 423. Etiology of the Dysen- 
teries of Manila. Circulars on Tropical Diseases, Manila, | and Il (1901). 
(3) Strong and Musgrave: Rep. Sur.-Gen. Army, Wash. (1900). Abstract in 
J. Am. Med. Ass. (1900), XXXV, 498 and 501. 
(4) Kruse: Ueber die Ruhr als Volkskrankheit und ihren Erreger. Deutsche 
med, Wehnsch. (1900), XXV1, 637. 
(5) Kruse: Weitere Untersuchungen iiber die Ruhr und die Ruhr _bacillen. 
Ibid (1900), XXVIT, 370 and 386. 
(6) Spronck: Eine kleine Epidemie von Pseudo-dysenterie bacillaris zu Utrecht. 
Baumg. Jahresb. (1901), XVII, 473 (1902), XVITT. 
(7) Flexner: A Comparative Study of Dysenteric Bacilli. Centrbl. f. Bacteriol. 
(1901), XXX, 449. 
(8) Vedder and Duval: The Etiology of Acute Dysentery in the United States. 
J. Bap. Med. (1902), VI, 181. Also Centrbl. f. Bakteriol. (1902), XXXI, 
148. 
(9) Duval and Basset: The Etiology of Summer Diarrheeas of Infants. Centrbl. 
f. Bakteriol. (1902), XX XIII, 52. Also Am. Med. (1902), IV, 417. 
(10) Park and Dunham: A clinical and bacteriological study of a number of 
outbreaks of Disease due to the Dysentery Bacillus of Shiga. NW. York 
Univ. Bull. Med. Sci. (1902), 187. 
