2AG The Philippine Journal of Science * 1922 
nodules of the ears and the reddish white patches were found bacteriolog- 
ically positive, and the septum of the nose was negative. 
The physical examination of the nose in February, 1922, showed catarrh, 
with the left side of the septum thickened, and the right side smooth 
and normal. A previous examination in November, 1921, gave negative 
findings on both sides of the septum of the nose (Table 2, No. 12). 
IlI.—A.C. (Table 3, No. 13), Filipino, 8 years old, female, born in 
Culion in 1913. Both parents living and lepers, residing in the Culion 
Leper Colony. There are two sisters: P., 7 years old, nonleper, and C., 6 
years old, and one brother S., 4 years old, who are considered clinically as 
lepers although they are bacteriologically negative. 
A. was isolated in the Negative Children’s House when 3 years old, 
and from there she was discharged after two and one-half years on 
account of the appearance of white patches which were suspicious of 
leprosy. There was no record made of the bacteriological findings at the 
time of her discharge. 
At present she shows white areas, with red circular patches in the center, 
on both cheeks and chin (Plate 5, fig. 2); one extensive, faint, whitish 
area on the left scapular region; and several white, reddish areas on the 
left ulnar region. There are no nodules or infiltration of the ears. On 
the left ulnar region and on the posteroexternal surface of both legs there 
is both thermal and tactile anesthesia. The legs are reddish and scaly, 
and there is ecthymatous itch over elbows, buttocks, thighs, and feet. 
The nose, examined in November, 1921 (Table 2, No. 23), showed inner 
aspect of right ala nasi with ulcer; superficial ulcer, anterior portion of 
septum, left side; corresponding portion of right side slightly swollen 
and with scab. 
The bacteriological examination in June, 1921, showed the nose negative 
and the skin positive; in November, 1921, both the nose and the skin were 
positive for B. leprz. . 
IV—A.M. (Table 3, No. 12), Filipino, 8 years old, female. Born in 
Culion. Both parents were lepers, now dead. No brothers or sisters. 
There is no reliable history obtainable on account of the death of the 
parents, but she says that the white areas appeared at the same time. 
Her condition on February 20, 1922, showed whitish areas of different 
shapes and sizes on chest, abdomen, back, and loin. The buttocks and 
legs showed the same color as the whitish areas, indicating that they consist 
of white confluent areas. The face was red and infiltrated. Both ears 
showed small nodules. The legs were red, dry, and scaly. There was ul- 
ceration on the right leg. The left forearm was also scaly. The white areas 
were not anesthetic, and in November, 1921, they showed sweating on 
administration of pilocarpine and hot tea. There is slight anesthesia on 
the anterior surface of the left forearm, both to temperature and to touch. 
The infiltration of the face and the nodules on the ears were not present 
on former examinations in June and September, 1921, when her picture 
was taken (Plate 4, fig. 8). There is also ecthymatous scabies on both 
legs and abdomen. 
The examination of the nose showed the right side of the septum 
with nodulelike swelling, the apex of which seems eroded and ulcerated, 
the left side of the septum being normal. 
Bacteriological examinations repeatedly made, June to November, 1921, 
showed the skin positive and the nose negative. On February 20, 1922, 
