2AS The Philippine Journal of Science 1922 
later both the ear infiltration and the face area disappeared after injections 
with ethyl ester of chaulmoogra oil and sodium cacodylate. P., 7 years 
old, female, is a positive leper (Table 8, No. 10). G., 3 years old, female, 
is negative. 
2—“C.” J., 9 years old, female, is a positive leper (Table 3, No. 16). 
D., 8 years old, female, is a suspicious leper, showing white area on the 
right loin and shiny legs. M., 7 years old, female, is negative. 
3.—‘N.” R., 10 years old, female, is a positive leper (Table 3, No. 
20). B., 7 years old, male, is negative. 
4—“C.” A., 8 years old, female, is a positive leper (Table 3, No. 13). 
P., 7 years old, female, is a nonleper. C., 6 years old, female, shows an 
extensive whitish area on and above right knee which is anesthetic to 
temperature but not to touch. S., 4 years old, male, shows whitish areas on 
back, above both knees, and on the right knee. 
5.—“D.” G., 5 years old, female, is a positive leper (Table 3, No. 6). 
L., 4 years old, female, shows small white spots on the right cheek and right 
arm, and flushed, shiny legs. S., 3 years old, female, sent away from 
Culion when about 5 months old. 
6.—“R.” There are five living children of a leper mother and a healthy 
father. J., 30 years old, female, and M., 20 years old, female, are lepers 
living now in Culion. Three younger brothers, aged 10, 9, and 7 years, 
respectively, are nonlepers and live in Tarlac Province. The mother, 
living in Culion, has borne another child by a leper father and this one, 
M. G., 4 years old, male, is now a positive leper (Table 3, No. 4). 
Leper lesions occasionally disappear spontaneously, as has been 
observed in one child, P.B., 5 years old, male, who was isolated 
in the Negative Children’s House and later was discharged for 
suspicious leprosy. In June, 1921, he presented a reddish infil- 
trated area on the left cheek which was_bacteriologically 
positive, but on February 20, 1922, and without treatment, the 
infiltration was negative. In our records there are four other 
children that showed, on first examination, bacteriologically 
negative white patches, but eight months later some or all of the 
patches disappeared. 
THE EFFECT OF SEGREGATION ON THE DEVELOPMENT OF THE DISEASE 
Since 1913 fifty-one children were transferred from Culion 
for adoption outside of the island. The age of the majority on 
transfer was between 4 months and 3 years; only one was 4 years, 
and another was 10 years of age. The children at the time of 
transfer were negative, physically and bacteriologically. 
So far three have been returned to the colony: two on account 
of leprosy, and one on account of the request of the father who 
is in the colony, as he thought the child was not being properly 
taken care of. 
The two children returned for leprosy were the following: 
G.M., male, born in Culion February 1, 1912; transferred away 
on March 23, 1914, at the age of 2 years and 2 months; on 
