126 The Philippine Journal of Science 1920 
examining at autopsy the first case of those that I am to report 
to-day. 
This was a male of 47 years, who died after a 10-day stay in 
the hospital. The clinical diagnosis was meningitis and acute 
nephritis. Autopsy was performed sixteen hours after death. 
The body was well developed and poorly nourished. 
The lungs were congested and showed areas of ecchymosis 
posteriorly, with here and there irregular patches of consolida- 
tion. The bronchi were congested and contained purulent 
exudate. 
The brain showed nothing of interest except a marked in- 
jection of the larger and smaller vessels over the entire surface. 
The heart showed slight enlargement and some myocardial de- 
generation. There was slight chronic nephritis. The aorta was 
slightly atheromatous. The rest of the viscera showed marked 
congestion. 
Anatomical diagnosis: Influenza; acute, purulent bronchitis; 
early bronchopneumonia; acute myocardial degeneration; dilata- 
tion of the heart; acute and chronic nephritis; congestion of the 
brain; moderate chronic splenitis; moderate arteriosclerosis. 
Cultures from the lungs were negative for influenza bacillus, 
and positive for a nonhemolizing streptococcus and for a 
diphtheroid. 
Histologically, sections from the different places of the cere- 
bral cortex passing through the internal capsules, the basal 
ganglia, and the peduncle showed marked engorgement of the ce- 
rebral capillaries. In a few there were found hyaline thrombi 
that contained polymorphonuclears.. Hemorrhages into the peri- 
vascular spaces were met with and many of the vessels were 
markedly infiltrated at the periphery and in the adventitia with 
small mononuclear cells, one, two, or three layers deep. It is 
not very unusual to find a slight amount of serous exudate, 
or delicate fibrils of fibrin around the blood vessels among 
which are seen the layers of infiltrating round cells. It is 
common also to see a layer of these white cells laid along the 
intima of the vessels. Not only are the perivascular spaces 
infiltrated, but in places, especially in those portions of the 
cerebral ganglia where the vessels show prominent changes, 
the surrounding nervous tissue as well is slightly diffusely infil- 
trated with round cells; at least these tissues look peculiarly 
different in being more cellular than portions not so infiltrated. 
In sections of the spinal cord the meningeal vessels ap- 
peared engorged and the meninges showed slight, diffuse, 
