ILLUSTRATIONS 
PLATE I 
Fig. 1. A maculo-papular lesion of three years’ duration on the cheek of 
a 6-year-old Filipina, which up to the present time is her 
only demonstrable lesion of leprosy. The spot, about 2 centi- 
meters in diameter, is slightly elevated above the normal skin 
surface; it is pink and contains numerous small nodules in 
which the causative organism can be found. A lesion of this 
character may remain practically unchanged for years; may 
almost entirely disappear, leaving a pale or pigmented, smooth 
spot; or it may grow progressively larger with the coincident 
appearance elsewhere of similar spots, as in fig. 2. 
2. Maculo-papular lesions of leprosy on each cheek and on the chin. 
3. An apparent latency of the macules of leprosy; which, in this 
case, are neither elevated nor nodular, but are smooth and faintly 
pigmented and as such cannot be distinguished from the _ 
numerous tinea, etc., that are frequently met with in the | 
tropics. In this and in the succeeding illustrations may be seen 
the progressive infiltration of the tissues over the inner half 
of the superciliary ridge, giving rise to overhanging eyebrows, 
suggesting a frown. Mention is frequently made of the loss 
of the hair of the outer half of the eyebrows as an early and 
diagnostic symptom of leprosy; this is not present in the cases 
shown in figs. 1 to 3. 
4. A case of leprosy, relatively older than those of figs. 1 to 3, 
showing a thinning of the outer half of the eyebrows as well 
as the early nodular infiltration of the nasal ale and the helix 
and lobule of each ear. 
5. A somewhat more advanced case of leprosy with a nodular infiltra- 
tion extending over the face. The nodules are small with the 
exception of one on the chin. Complete loss of the hair of 
the outer half of the eyebrows is here shown. A small amount 
of edema of the eyelids is present. ; 
6. The nodules are larger and more prominent than in the preceding 
eases. This and figs. 7 to 9 illustrate the loss of normal contour 
of the nose from the destruction of cartilaginous tissue. 
. 7. In addition to the diffuse infiltration of the face, there are 
well-marked infiltration of the lips and slightly pendulous ear 
lobules. 
8. The nodules, as discrete tumors, are surrounded by apparently 
normal tissue. A considerable loss of the cartilage of the tip 
of the nose has caused a marked flattening of this appendage. 
9. Illustrating shotlike tubercles of leprosy as discrete nodules, 
scattered over the entire face; the arms and the legs, and to a 
lesser extent the trunk, showed similar tumors. 
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