XIV, 1 Lantin: Treatment of Typhoid Fever 33 
therapeutic agent, and they have drawn others into the ranks. 
Among the leading investigators in this field, according to Gay . 
and .Chickering,(11). are Ardin-Delteil, Negre and Raynoud, 
Boinet, Delearde and Leborgne, Sable, Netter, Roques and Al- 
faro, Feistmantel, and Garbat. 
In this series there were ten cases treated with sensitized 
typhoid vaccine intramuscularly, and the series was treated just 
after the series of cases treated intravenously with sensitized 
vaccine. 
TABLE IX.—Condition of patients before treatment. 
Severe and toxic 
Severe and nontoxic 
Mild 
bet Q 
Total 
Mode of treatment.—The sensitized typhoid vaccine, as stated 
previously, was administered intramuscularly. The dosage em- 
ployed was from 250 to 1,000 millions every three or four days. 
Gay advised 800 millions every other day and Garbat 500 millions 
every five or six days. The results of this treatment upon the 
course of the disease are shown in Table X. 
TABLE X.—Sensitized typhoid vaccine administered intramuscularly. 
j 
Cases. 
Dey § | Dura- | Dura- 
Classification by results. Severe | severe Total. — peed 3 i povthed 
mild. | 224 |" and ment. | ent. 
toxic. toxic. ‘ 
Days. ; Days. 
AbOtte -sis e ee See eas 4 0 0 4 10 $.2| 13.2 
Bene tee fe. Se as aa Ses 0 2 0 2 16 11.0) 27.0 
Relatively unaffected .._-.-....---.--.- 0 1 0 1 11| 32.0} 43.0 
PONG a er ee 8 Se ak meee nies Seu tens Deeg 
Cridias. 22) oe eee es ee te ee ee pe PERE aor) © einer Siar oie 
RR RSE See inp ee Ie mh Renae Mn as Oy Geren on bier ha! alert S ae eet 
PVerage oo a oo a a ee aes capes 27.7 
x. 
Thus, it may be seen that there were four abortive cases, all 
observed in the beginning of the second week, and all of them 
mild, in which the average duration of the disease was 13.2 days; 
two benefited cases, during the third week, both of the severe 
and nontoxic type, with twenty-seven days as the average dura- 
tion of the disease; and one relatively unaffected case of the 
same type as the benefited cases, with forty-three days as the 
average duration of the disease. The total average duration of 
