xiv.2 Haughwout and de Leon: Erythrocyte Ingestion 217 
phenomena observed by us occurred in a child may have some 
significance in view of the well-known virulence of protozoal 
infections in children and in young animals. Mello-Leitao(10) 
lays particular stress on the virulence of flagellate infections 
in children and states his belief that the most frequently oc- 
curring type of dysentery in infants is of flagellate origin. 
In the cases reported by Derrieu and Raynaud, and by 
Chatterjee, the bowel movements were dysenteric in character, 
as in our case. Derrieu and Raynaud also reported 14 per cent 
mononuclear leucocytes on the differential blood count. The 
mononuclear count is almost always of interest in protozoal 
infections, but unfortunately they say nothing in connection 
with their case as to the possibility of a concurrent malaria. 
It has occurred to us that Pentatrichomonas may be the etio- 
logic factor responsible for the outbreaks of so-called “epidemic 
flagellate dysentery” reported by so many workers in the tropics 
and elsewhere. On this point, Derrieu and Raynaud in their 
paper say: 
Nous devons signaler le caractére épidémique de cette variété de dysen- 
terie. Notre malade nous a affirmé que les cas de diarrhée dysentériforme 
étaient nombreux dans la contrée qu’il habitait: certains de ses compagnons 
avaient gardé cette diarrhée pendant plusieurs mois, mais aucun n’avait 
été aussi gravement attreint que lui. I] nous a été impossible de faire une 
enquéte sur place, 4 cette époque; elle aurait donné lieu tré probablement 
& de curieuses constatations. 
We also have in mind a supposed epidemic of flagellate dy- 
sentery at Parafiaque, near Manila, in 1914, and mentioned by 
one of us,(8) in which many deaths occurred and for which 
no other cause except a trichomonad infection could be found. 
We do not see the necessity for discussing at length the 
treatment of trichomonad infections. Suffice it to say that 
Derrieu and Raynaud claim to have cured their case by the ad- 
ministration of turpentine, by mouth and by enema. This is a 
form of treatment advocated in 1913 by Escomel, who later(6) 
used the same treatment in vaginal infections and introduced 
another treatment with iodine solution, either of which he claims 
will cure all cases. Derrieu and Raynaud noted the inefficacy 
of ipecac, collargol, neosalvarsan, urotropin, and sodium sul- 
phate in their cases. Castellani has reported encouraging re- 
sults, in some instances, in the treatment of flagellate infections 
with methylene blue. 
Chatterjee seems to have met with poor success in the eme- 
tine treatment of his cases of dysentery associated with Penta- 
trichomonas infection. Only one of those he cites seems to have 
