640 Philippine Journal of Science 1920 
were cut from the same blocks and also from blocks that 
contained apparently undamaged tissue, but the search for 
balantidia was still fruitless. We also failed to find balantidia 
in blocks of the tissue that was fixed in Zenker’s fluid. Need- 
less to say, we found no parasites in the lung, liver, or other 
viscera. 
As stated in the beginning, it is not our intention at this 
time to describe in detail the pathological changes observed 
on study of our preparations. While we failed to find para- 
sites in their customary habitat or, indeed, in other localities 
where we have found them in other cases, we certainly discov- 
ered in the intestine what we, at present, are inclined to inter- 
pret as unmistakable evidence of their former presence. But 
some of the points involved are too fine to warrant any positive 
statements on our part until we have gone over the material 
repeatedly and cut new sections and compared them with sec- 
tions cut from other cases. Then we may be able to add some- 
thing definite to what is already known concerning balantidiosis 
in man. 
The general microscopic picture presented by our sections 
was cloudiness of the muscular coat and moderate injection of 
the blood vessels. There was some cedema of the submucous 
coat and of the interglandular “tissues, with slight diffuse infil- 
tration of the superficial mucosa with polymorphonuclear leuco- 
cytes and a moderate number of plasma-cells. The material 
showed a catarrhal colitis, with some very superficial ulcera- 
tions accompanied by slight secondary infection. 
In any event, it cannot be said that our failure so far to 
discover balantidia in the tissues was due to their destruction 
by post-mortem changes, for our tissue was fixed, and well 
fixed, within one and a half hours following the death of the pa- 
tient. Balantidia in a fair state of gross preservation have 
been found in tissues fixed twelve hours and more after the 
death of the patient. Our material, particularly that portion 
fixed in Bouin’s fluid, was in excellent condition, and there was 
remarkably little shrinkage of the glandular elements. 
Aside from the interest it holds to the student of the problems 
connected with protozoal dysentery, this case is of interest to 
the clinician, by reason of the fact that the treatment of balan- 
tidial dysentery in the past has been anything but satisfactory- 
The ipecacuanha compounds seem not to be as efficacious as 
they arb in entamebiasis, and other modes of treatment have 
been disappointing. If it is possible in subsequent cases to se- 
