iSS Vaccine Imculation. 



that the vaccine inoculatioii is a perfed fecurity againft ikt 

 finall-pox. 



^^ ift, By the dire«9: of indlrc^i communication wticb all 

 our inoculated patients had with a great number of childfeh 

 attacked with the fmall-pox in every quarter of the city. It 

 is well known that the fmall-pox is infectious long after th^ 

 patients are in a condition to go abroad. Van Swieten elli^ 

 mates that the difeafe is Hill capable of communicating it- 

 f(;lf fixty days afterjt has made its appearance ; but moll pa- 

 tients^ after the twentieth day, go about as ufual in thellreets 

 and public places, and wherever their b.ufmefa or occupa- 

 tions may lead them. It is impoflible, therefore, that nearly 

 four hundred children, inoculated for the vaccine four months, 

 ago, fliould have all efcaped if they were fufceptible of infcc-? 

 tion from an epidemic diftemper fo general as that which 

 prevails here at prefent, and to which 150 children have- 

 fallen a facrifice within our walls. None of them, however, 

 have had the fmall-pox except four, who certainly had thtj 

 germ of the difeafe before they were inoculated. 



^' ad. We have even inoculated the fmall-pox from arm 

 %o arm, and with all the precaution neceffary to infure the 

 fuccefs of the operation, on ten or twelve of thofe inoculated 

 with the vaccine, and feven weeks after, the fears of the vac- 

 cine had dropped off; but none of them fhowed the leaft 

 fymptpm of general infedion. The incifion became lightly 

 inflamed j hut it fpeedily dried up without areolae, and with-- 

 out any appearance of fever. 



ff We have acquired alfo, by repeated trials, the moft 

 complete proof that the vaccine is not a contagious difeafe. 

 In f(pveral families we have inoculated two, three, or four 

 children after each other. Thofe who had the difeafe flept 

 with fome who had not h^en inoculated, and the latter were 

 not affeCled till they were inoculated in their turn. In other 

 refpe6l:s we faw no inftance of contagion. 



" liliall add,'- fays Dr, Oder, " that it did not appear to 

 Its that the inoculated vaccine was followed by any other 

 malady; neither pjmples nor eruption, ne^itber for* eyes nor 

 bad ears, nor any accunwlations of matter fo often obferved 



after 



