308 National Vaccine EstalUsh?kenl. 



exhibited uncombined, in which state it is not attended 

 with any particular inconvenience. 



It is well known that taenia may exist in a healthy state 

 of the system; and that hence its presence cannot be ac- 

 curately ascertained by any other circumstance than the 

 actual discharge of portions of the worm itself. Some- 

 times, indeed, there is felt a heavy pain in the epigastrium, 

 attended with dyspepsia and emaciation; but these are not 

 pathognomonic symptoms, as they may arise from other 

 causes. 



fTo be continued.] 



LIX. Intelligence and Miscellaneous Articles . 



NATIONAL VACCINE ESTABLISHMENT. 



JL he Board appointed by His Majesty's Government to 

 regulate the affairs of this establishment has ordered that 

 the following description of the vaccine vesicle, and in- 

 structions relative to vaccination, which have been pre- 

 sented by the director, be strictly observed by the vacci- 

 nating surgeons. 



Description of the regular Vaccine Vesicle. 



When vaccination succeeds, a small red spot is observa- 

 ble on the third day, the day the operation is performed 

 being reckoned the first. If the spot is touched, an eleva- 

 tion is felt ; and if examined with a magnifying glass, the 

 little tumour appears surrounded l>y a very slight efflores- 

 cence. 



The spot gradually enlarges ; and between the third and 

 sixth day a circular vesicle appears. The edge of the vac- 

 cine vesicle is elevated, the centre depressed. The colour 

 is at first of a light pink, sometimes of a blueish tint ; and 

 changes by degrees to a pearl colour. The centre is some- 

 what darker than the other parts. 



The vesicle is hard to the touch. 



In its internal structure it is cellular; the cells being filled 

 with transparent lymph. 



The vesicle commonly augments till the tenth or eleventh 

 day. 



In the early stages, there is usually round the base an 

 inflamed rirg; or this takes place on the seventh or eighth 

 day; towards the ninth it spreads rapidly, and near the 

 tenth forms an areola of about an inch and a half in diameter. 



This areola is of the usual colour of inflamed skin; it is 

 bard, and accompanied with some degree of tumefaction. 



H 



