THE HAEMOFLAGELLATES 



well-marked myonemes. Prior to gamete-formation, both gametocytes 

 come into relation with the leucocytes, in an unusual manner (see 

 under " Habitat," p. 205), and lose all trace of locomotor organellae. 



Microgamete - formation, maturation 

 and fertilisation of the megagamete 

 (Fig. 27), in the gnat, present nothing 

 unusual. Instead of an ookinete 

 giving rise to a single Trypanosome, 

 as in Trypanomorpha, it grows con- 

 siderably, forming a large coil, and 

 nuclear multiplication goes On actively 

 at the same time (Fig. 28). Ulti- 

 mately, an enormous number of little 

 spirochaetiform parasites are pro- 

 duced, which populate the alimentary 



tVip crnnl- 

 l6 nat> 



^f *V>^ , r.v.l^'k'l^ ^,V 



of this remarkable work 



FIG. 27. 



Fertilisation of a megagamete by a 

 microgamete. The trophic and kinetic 

 female pronuclei are seen on the left. 



Near the middle lie the two reduction- 



nuclei. The remains of the host -ceil j s based mainly upon the realisation 



together with the cast-off envelope of . f i 



(After that, in SUcll a Complicated Study, 

 ,, /. ,-, 



there was a grave source of possible 

 error, and there is nothing to show that this was eliminated. 

 The opinion has been very generally expressed that Schaudinn 

 did not sufficiently guard against the liability of confusing and 

 mixing up the life -histories of entirely distinct parasites. In 



the parasite are on the right. 

 Schaudinn.) 



c. 



FIG. 28. 



Growth and metamorphosis of an indifferent ookinete ; in C nuclear multiplication is well 

 advanced. (After Schaudinn.) 



the first place, it is said that in the species of owl used at least 

 four separate Haematozoa occurred : two free parasites, namely, 

 a Trypanosome and a Spirochaete (" Trypanosoma " ziemanni) 

 and two intracellular ones, a Halteridium and a Leucocytozoon. It 

 may be at once admitted that this is quite possible. At any rate, 

 the entire subject is reopened and cannot be settled definitely until 



