216 THE SPOROZOA 



stance being given off from the karyosome into the linin framework. 

 At the same time the outline of the nucleus becomes irregular and 

 indistinct, and it soon begins to send out processes into the cyto- 

 plasm, forming paths along which the chromatin-granules wander 

 out and travel towards the periphery of the body of the gametocyte. 

 They reach ultimately the most superficial layer of protoplasmic 

 alveoli, leaving the pallid karyosome, now almost deprived of chro- 

 matin, in solitary state at the centre of the body of the gametocyte. 

 At first scattered evenly, the minute chromatin-granules soon collect 

 together and become concentrated into patches disposed at more or 

 less regular distances from one another over the surface of the cell 

 (Fig. 51, VII $\ In each patch the chromatin-granules draw 

 more closely together and fuse into a dense mass of chromatin, 

 which at first has the form of an irregular tangle, but soon becomes 



$&k 



chr. 



fc' 



V 



FIG. 52. 



Division of the nucleus of the schizont of Coccidium schuberyi, Schaiul. (par. Lithobius 

 forficatug), in schizogony. After Schaudinn [51]. a, resting nucleus, with karyosome (ky) and 

 chromatin-granules (chr). b, the karyosome commences to divide, c, the karyosome forms 

 a dumb-bell-shaped figure, round the two extremities of which the chromatin is aggregated. 



d, complete division of the karyosome, and separation of the chromatic portions of the nucleus. 



e, complete separation of the two daughter nuclei. 



a compact lump of chromatin enclosing a single clear vacuole. The 

 nuclei so formed become lengthened and drawn out so as to be first 

 comma-shaped, arid then elongated and filamentous in form (Fig. 

 51, VIII $ ) ; each nucleus bends upwards so as to project from 

 the body of the gametocyte, enveloped in a sharply-limited zone of 

 hyaline protoplasm, from which two flagella grow out ; active move- 

 ments are at once set up by the flagella ; and finally the nucleus 

 breaks loose with its protoplasmic envelope and flagella, and is set 

 free from the gametocyte as the minute and extremely active micro- 

 gamete, the male element in conjugation. The microgametes swim 

 off and swarm away in quest of the macrogametes, leaving the 

 body of the microgametocyte, which is not sensibly diminished in 

 bulk by subtraction of the microgametes, and which, with the 

 karyosome still in its heart, is abandoned as residual protoplasm, 

 and soon breaks up and dies. It is evident that the formation of 

 microgametes is nothing more than a peculiar type of schizogonous 

 generation, which differs in certain points, both of method 1 and 



1 But the method is subject to variations in both cases, in Coccidia generally, and 

 the difference between the formation of the microgametes and ordinary schizogony 



