Kx\i INTRODUCTORY LETTER TO SENATOR MOSSO 



answer to the inquiry is to be expected. To return : 

 we have seen that if we do not compare the same 

 individuals with one another we cannot be sure of 

 correctly measuring the phases of growth. As guinea- 

 pigs nearly complete their growth in one year, it was 

 possible to make the requisite number of observations 

 within a reasonable period, which is not the case with 

 man. 



In regard to my studies on the structure of cells in 

 relation to growth, nothing special as to methods is 

 to be said, as I have employed only the well-known 

 standard procedures of histologists and embryol- 

 ogists. 



If the conclusions formulated in this book con- 

 cerning cytomorphosis, senescence, and rejuvenation 

 are correct, they will have direct bearing on many 

 lines of investigation concerning growth, reproduc- 

 tion, regeneration, degeneration, and pathological 

 changes. If the conclusions are correct they will 

 open, I hope, the way to many new interpretations. 

 But I must stop. 



Let me, however, close this lengthy letter with the 

 request that you accept the dedication of this volume 

 as a memento of our long friendship, and as an 

 expression of my admiration and attachment. 

 Yours faithfully, 



CHARLES SEDGWICK MINOT. 



HARVARD MEDICAL SCHOOL, 

 BOSTON, MASSACHUSETTS, Jan. 13, 1908. 



