7 6 AGE, GROWTH, AND DEATH 



to us the variations in the death of cells and in their 

 modes of removal which are known at the present 

 time. These tables are taken from a lecture which I 

 delivered in New York a few years ago, and which 

 was subsequently published. 1 If any of you should 

 care to make a closer acquaintance with them they 

 are therefore readily accessible to you. 



In order to render the nature of cytomorphosis 

 clearer to you let me ask your attention for a concrete 

 example, the biological history of the red blood cor- 

 puscles, minute bodies, which in man are normally cup- 

 shaped, 2 as they are in various other mammals also. It 



(c) Imbibition. 

 (</) Desiccation. 



(e) Clasmatosis. 

 (2) Nuclear changes : 



(a) Karyorhexis. 



(b) Karyolysis. 



B. Hypertrophic degeneration. 



(1) Cytoplasmic : 



(a) Granular. 



(b) Cornifying. 



(f) Hyaline. 



(2) Paraplasmic : 



(a) Fatty. 



(b) Pigmentary. 

 (<r) Mucoid. 



(d) Colloid, etc. 



(3) Nuclear (increase of chromatin). 



1 "The Embryological Basis of Pathology," the Middleton Goldsmith Lecture 

 delivered before the New York Pathological Society, March 26, 1901, Science, 

 xiii., 481-498, and Boston Med. Sur. Journal, cxliv., 295-305. 



It was in the course of this lecture that the law of cytomorphosis was first 

 publicly announced and formulated. 



3 The form usually ascribed to them is that of a biconcave disc, a shape which 

 appears to be a post-mortem artefact. The true shape was first proven by 



