338 THE VITAMINES 



measure. This therapy was used in Germany by Moro (1200), in 

 the form of carrot soup, with good results. A similar therapy was 

 recommended by Stark (1201) in suspected avitaminoses, and 

 recently, there has been a similar report by Aron and Samelson (1202). 

 McClendon and Sedgwick (1202a) used spinach powder in infant 

 nutrition and obtained satisfactory increases in weight. Aron 

 (1202b) made use of the soluble flour obtained by the action of 

 ferments and found that such products were well utilized in the 

 more severe cases. 



From time to time, there appear in the literature statements as to 

 a successful vitamine therapy in certain disturbances. Kohlbrugge 

 (1203) successfully treated cholera infantum, a disease generally 

 regarded as an infection or intoxication, with orange juice. Holt, 

 Courtney and Fales (1204) treated a case of intestinal infantilismus 

 with cod liver oil, with good results. 



It need hardly be said that in the feeding of children, the same 

 rules are to be observed as have already been formulated for animals. 

 Besides the already known dietary constituents, we must provide for 

 the presence of the three known vitamines. It is also essential that 

 the more important constituents should not occur in the diet in too 

 great a dilution. Some of the recorded therapeutic results with 

 vitamines depend upon the fact that either the certain vitamines, 

 although they were present, were not sufficient, or the relative propor- 

 tion of the individual food constituents to each other was not quite 

 correctly chosen. Weill and Mouriquand (1205) have pointed out 

 such a possibility; as regards vitamine B in this connection, we have 

 the work of Daniels, Byfield and Loughlin (1206). We may explain, 

 in this way, certain results of vitamine therapy in an insufficiently 

 defined condition, usually called "marasmus" or "malnutrition." 

 Eddy and Roper (1207), and Dubin and Lewi (I.e. 628) obtained 

 marked results in the conditions just mentioned. 



As regards atrophy, it is caused by excess of fat, according to the 

 present conception. The results of Friedberg and Noeggerath (1208) 

 are to be regarded in this light; they recommended the use of centri- 

 fuged breast milk in this condition. This recalls certain investiga- 

 tions on rats, made by Funk and Dubin (I.e. 331). These animals 

 received a complete synthetic diet, containing more than 50 per 

 cent fat. The young rats were able to live on this diet for 2 to 3 

 months. In spite of the vitamine content of the diet, the animals 



