360 THE VITAMINES 



cytes and a decrease in polymorphonuclear neutrophiles. Micro- 

 scopic findings were recorded by Nagamatsu (1323). Examination 

 of the cerebrospinal fluid, according to Lorenz (1324), gave no reason 

 for regarding pellagra as an infection of the central nervous system. 

 The heart is mostly atrophic, pigmented, fragile and occasionally 

 shows fatty degeneration. Sometimes there is lung edema, hyper- 

 emia and hydrothorax. 



FIG. 72. RARIFICATION OF THE PHALYNGEAL ENDS IN PELLAGRA (ROBERTS) 



5, Bones 



Lombroso (1325) and Babes and Sion (1326) observed, in some 

 cases, brittleness of the ribs and long bones. Fractures of the long 

 bones were also noted. Similar lesions are characteristic of human 

 and experimental scurvy. Roberts (I.e. 1281) gives some X-ray 

 pictures of pellagrous bones, showing a ratification of the bone ends. 



6. Sexual organs 



In acute cases, vulvo-vaginitis is not infrequently observed, and 

 in rare cases, there is gangrene of the labia. In chronic cases, amen- 

 orrhea frequently occurs. Abortion was noted in 20 per cent of 



