368 THE VITAMINES 



Infantile pellagra, as for example in the case described by Voegtlin 

 and Harries (I.e. 1304), might be of help in clearing up the etiology. 

 It is indeed true, according to Eckles, Palmer and Swett (1383), 

 that the protein content of the milk can be influenced by nutrition 

 to a certain extent; still, the possible variations could hardly explain 

 the occurrence of infantile pellagra, of which some instances have 

 been observed. 



We are inclined to the view of Goldberger (I.e. 109), who con- 

 sidered the following etiological factors as possible : 



1. Partial lack of vitamines. 



2. Lack of animal protein. 



3. Lack of a still unknown vitamine. 



4. The combined influence of all these factors. 



We believe that the dilution of protein with carbohydrates increases 

 the vitamine requirements, so that although the vitamines are 

 present, they do not suffice. We have mentioned the possible 

 significance of the important substance, associated with proteins, and 

 it is not impossible that this factor is lost during the milling of corn. 

 It would be rather premature to consider the chapter of pellagra as 

 closed. 



