THE VITAMINES IN THE ANIMAL KINGDOM 



123 



of which by chance may supplement each other. In our earlier work, 

 we believed at first that we could conclude from the symptoms (dis- 

 position to bleeding, petechiae and rosary) and from the favorable 

 influence of orange juice, that we were dealing with an antiscorbutic 

 vitamine deficiency. Macallum (341) later adopted the same view. 

 Recently, there appeared the papers of Harden and Zilva (I.e. 100) and 

 Drummond (I.e. 79) completely corroborating the above observa- 

 tions. Still, some doubt has lately arisen, since Osborne and Mendel 



210 



180 



150 



err 120 



o 



90 



60 



FUNK 



/ 



OSE 



MENDEL 



)RNE 



DAYS 



M C COLLUM 



30 



FIG. 28. COMPARISON OF NORMAL RAT GROWTH CURVES OF OSBORNE AND- 

 MENDEL, McCoLLUM, AND FUNK 



(I.e. 92) as well as Byfield, Daniels and Loughlin (I.e. 90), showed that 

 vitamine B is found in appreciable quantities together with vitamine 

 C in fruit juices. This is in agreement with our latest observations, 

 noted in our work with Dubin, that rats on a diet containing sufficient 

 vitamine nevertheless show improvement upon the addition of extra 

 vitamine. Besides, in our earlier and later work we have often found 

 that an addition of freshly prepared dietary mixture is followed by 

 marked stimulation of growth. 



