164 PHYSIOLOGY 



"Parathys." The males are not affected. The effects in the 

 females are similar to those in the "Thypars" but in less degree. 

 Table 117. 



Effect on the glands of internal secretion (Hammett, '23}. "Thy- 

 pars." In the male the growth of the hypophysis is accelerated. 

 Absolute cessation of growth and a high degree of retrogression 

 is shown by the adrenals, pancreas and thymus. The thymus is 

 most affected. 



In the female the growth of the hypophysis is retarded, but the 

 other glands are affected as in the male. 



"Parathys." In the male there is retardation of growth in the 

 hypophysis , adrenals, pancreas and thyroid. The thymus shows a 

 considerable degree of retrogression. In the female the effects 

 are similar, but more marked than those in the male, except in the 

 case of the hypophysis table 117. 



Effect on the viscera (Hammett, '22 and '23}. "Thypars." In 

 the male there is absolute inhibition and also retrogression in the 

 growth of the heart, lungs, liver, kidneys and spleen. Growth 

 in the submaxillaries is stopped. 



In the female the effects are as in the male, except in the case 

 of the liver. The retrogressive changes are more marked in the 

 female. 



"Parathys." In both sexes there is inhibition only, except 

 in the spleen and submaxillary, which grow excessively. 



Effect on the refractive index and water content of the blood serum 

 (Hammett, '23}. "Thypars." Male rats show a decrease in the 

 water content of the serum and an increase in the refractive index 

 of such a nature as to allow the conclusion that a true partial 

 desiccation of the serum has occurred without a great alteration 

 in the nature or distribution of the refractive solutes. 



In female rats the operation produces a state of partial inani- 

 tion, the effect of which on the serum is to counterbalance the 

 desiccatory effect of the thyroid loss when growth in body weight 

 occurs after such a loss. 



"Parathys." The effects are the same for both sexes. There 

 is no alteration in the concentration of total solids of the blood 

 serum which appears when the rats are 150 days old; There is a 



