44 CHARLES F. W. McCLUEE 



It lias previously been demonstrated (fig. 6) that, when the 

 inside of the skin is turned outward, the direction in which 

 fluid is transported through the skin is exactly opposite to 

 that in which fluid is transported when the outside of the skin 

 is turned outward. If the presence of K in the Ringer's solu- 

 tion influences the rate at which fluid is transported inward 

 through the skin into the glove, when the outside of the skin 

 is turned outward, it is evident that the rate at which fluid 

 is transported outward through the skin from the glove when 

 the inside of the skin is turned outward should be similarly 

 influenced. Such has been found to be the case, as is shown 

 by the following experiments which are of the same type as 

 the preceding experiment (exper. 567, fig. 17). 



Experiment 553 (fig. 18) 



Two skin gloves removed from the hind legs of the same 

 frog (R. pipiens), with the inside of the skin turned outward, 

 were filled, one with Ringer and the other with Ringer minus 

 K, and were then suspended, respectively, in Ringer minus 

 K and Ringer. (For type of experiment see diagrams C and 

 D in fig. 18.) Four experiments of this character were made, 

 and in each instance, after the usual initial gain in weight 

 during the first hour's suspension, the glove containing 

 Ringer minus K (D in fig. 18), when suspended in Ringer, lost 

 more in weight during the course of twenty-four hours than 

 did the glove containing Ringer when suspended in Ringer 

 minus K (C in fig. 18). 



Another type of experiment which differs from that of the 

 preceding experiments follows. 



Experiment 565 (fig. 19) 



The right and the left skin gloves of the same frog (R. pi- 

 piens), with the outside of the skin turned outward, were filled, 

 one with Ringer and the other with Ringer minus K, and were 

 then suspended in Ringer minus K. (See diagrams E and F 

 in fig. 19, which indicate type of experiment.) Four experi- 



