LYMPH FLOW 39 



course of twenty-four hours. In such cases the lymph spaces 

 and the pleuro-abdominal cavity were filled with fluid, and 

 the stomach, bladder, and intestines produced an abundant 

 secretion. Gunzberg found also that skin gloves filled with 

 Ringer and immersed in a liquid with an excess or absence 

 of K, increased in weight, while the weight of a glove filled 

 with Elnger minus K and immersed in Ringer diminished. 



In the light of the experiments described in the preceding 

 pages, the writer has made a detailed study of the results 

 obtained by Gunzberg. The results obtained by him would 

 seem to indicate that the force by which fluid is transported 

 through the skin, independently of osmotic pressure, may 

 be regarded in the light of an electrical phenomenon. 



A number of experiments were made on skin gloves, with 

 the outside of the skin turned outward, as well "as inward, to 

 determine the rate of transport of fluid through the skin, in 

 relation to the presence or absence of K both in the Ringer 's 

 solution contained in the glove and also in the solution in 

 which the glove was suspended. Skin gloves removed from 

 the hind legs were used ; the glove from the right leg was, as 

 a rule, used for the control and the glove from the left leg 

 of the same frog was used for the experiment. Also, as in 

 all of the preceding experiments, the gain or the loss in 

 weight of "the glove was based on the original weight of the 

 empty skin glove, before fluid was placed in the glove, and 

 prior to the suspension of the glove in the solution. The 

 results of these experiments are graphically shown in figures 

 15 to 23, inclusive. The variability observed in the behavior 

 of different skins in the same type of experiment, in relation 

 to the rate at which fluid is transported through the skin 

 independently of osmotic pressure, is analogous to that pre- 

 viously described as commonly existing among skins obtained 

 from different animals (figs. 1 to 4, inclusive). A knowledge of 

 this variability for skins in general has therefore made pos- 

 sible a correct interpretation of the variable conditions ob- 

 served in these experiments. 



