GENETIC TYPE AND THE ENDOCRINES 713 



Text-fig*ure 126 shows the course of the effect of hypo- 

 physectomy upon the salivary C-R. It will be seen that the 

 response, normally vigorous and regular in appearance during 

 3 months, was completely absent in every test after the gland 

 was removed. 



Figures 1 and 2 in plate 111 show the records of the motor 

 C-R before and after the operation. In figure 1 before the 

 operation, note the vigor of the head movements, the change 

 in respiration and the quick defensive raising of the paw 

 when the tone of 256 cycles was sounded. In figure 2, for 

 the post-operative period, note the slow lowering of the head, 



PITUITARY EXPERIMENT 



DOG 492* % BASSET-SHEPHERD 



SALIVARY CONDITIONED REFLEX 



Text-figure 126. A chart of the effect of complete hypophysectomy on the 

 conditioned salivary reflex in dog 492. The response to the Met. 120 disappeared 

 completely. 



slight alteration in breathing, and the absence of the condi- 

 tioned leg movement. In this animal, even the shock failed 

 to evoke a movement of the leg. 



The detailed course of the motor C-R throughout the 

 several phases of the experiment can be seen from text-figure 

 127. This chart indicates the disappearance of the response 

 almost immediately following the operation; there was no 

 reappearance except on one occasion, when no gland material 

 was being administered. During the last month of the ex- 

 periment, attempts to restore the response by extracts were 

 only partially successful. A slight enhancement of the magni- 



