VIL] MICROCOCCUS. 65 



smaller than the sarcina ventriculi, and when in large 

 quantities have a yellowish tinge. Like the sarcina ventriculi 

 they are in groups of four, and these again occur in larger 

 or smaller aggregations and zoogloea. I have cultivated 

 them successfully through many generations in pork broth, 

 beef broth, mixture of gelatine and broth, at ordinary 

 temperatures and in the incubator ; more easily however 

 at ordinary temperatures. 



(d) Pathogenic micrococci. Many of these are associated 

 with disease. In the pus of open wounds, 1 and in that of 

 closed abscesses, occur micrococci, singly, in dumb-bells, 

 and in colonies or short chains, 2 but there are certain acute 

 inflammations, e.g. that produced by subcutaneous injection 

 of turpentine, the pus of which does not contain micrococci 

 or any other organism. 3 



The secretion of open ulcers, such as occur in ordinary 

 acute inflammations of the skin and mucous membranes, in 

 ulcerations of the throat due to scarlatina, in every ulceration 

 of the intestinal mucous membrane, in the lymph of the 

 vesicles of the skin and mucous membranes of the mouth 

 occurring in various kinds of inflammations, there are almost 

 always present micrococci in dumb-bells, often also in 

 beautiful chains. In the ulcers and abscesses they often form 

 continuous masses, i.e. zooglcea, encroaching upon the tissue 

 of the base of the ulcer. To this category belong the 

 minute micrococci (about 0*0005 mm. in diameter) which 

 Klebs described as microsporon septicum, found in and 

 around wounds. The spread of purulent inflammation in 



W. Cheyne, Path. Trans, vol. xxx. 



2 Ogston, " Micrococcus in Acute Abscesses," Brit. Med. Journ. 

 March 12, 1881. 



3 Uzkoff, Virchow's Archiv, vol. 86, i. p. 150. 



