VIL] MICROCOCCUS. 73 



only accessory. 1 Cultivations and inoculations with pure 

 cultivations of this micrococcus are still wanting. 



4. Micrococcus pneumonia. In acute croupous pneumonia 

 there occur in the affected lungs large numbers of micrococci ; 

 Klebs, Eberth, Koch, Leyden, and others have seen them, 

 but Friedlander 2 first pointed out their constant occurrence. 

 According to this observer they are oval, each possessed of a 

 capsule, about o'ooi mm. long, and occur in the sputum 

 singly, but especially as dumb-bells or diplococci, as chains, 

 and as zooglcea. Ziehl 3 found them in very large crowds in 

 the sputum, giving to this in the early stages the peculiar 

 characteristic brownish " prune-juice " tint. But this state- 

 ment cannot be correct, since this tint may be very pro- 

 nounced although the sputum contains only a limited number 

 of the micrococci. According to this observer, they are very 

 numerous only in the beginning of the illness ; after the 

 critical stage they decrease in numbers. 



Grifrlni and Cambria saw the micrococci also in the blood. 

 Salvioli found that their number increases after the third day ; 

 on the ninth or tenth day they quite disappear. 



G. Giles 4 found them in many cases of pneumonia (in 

 India), both in the sputum and in the blood. Cultivations on 

 boiled potato yielded good crops. These cultivated micro- 

 cocci injected into the subcutaneous tissue of rabbits produced 

 pneumonia. 



Salvioli and Zaslein 5 cultivated the micrococci (derived 



1 Compare also Klebs, Archiv f. exp. Path. iv. ; Letzerich, Vtrcfoixfs 

 Archiv, vol. 68; Nassiloff, ibid. vol. 50; Eberth, Zur Kenntniss -d. 

 bact. Mycosen, 1872 ; Wood and Formad, Report of National Board of 

 Health, U.S.A. 1882. 2 Virchovfs Archiv, vol. 87. 



3 Centralb. f. med. Wiss. No. 25, 1883. 



4 Brit. Med.Journ. July 7, 1883. 



5 Centralb. f. med. Wiss. No. 41, 1883. 



