GROWTH AFTER INANITION FOR VARIOUS PERIODS. 



of suppression is due to specific histological changes in the ductless 

 glands, as suggested by Osborne and Mendel ('16). 



In part, however, especially in the first few days of refeeding, 

 the apparent increase in body weight is due to increase in contents 

 of the alimentary canal (and possibly also in the circulating 

 media of the body), which represent increase in gross body weight, 

 but not actual growth of the tissue-cells. 



220 



200 



i So 



m 

 1 



o 



*j I2O 



M 



!? 



j 100 

 >> 



"S 80 

 pq 



60 

 40 



20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 



Age in Days 



CHART D. Females. Chart showing the curve of growth of the test females 

 refed after maintenance from three to ten weeks of age, superimposed upon that 

 of the control females, so that the starting points coincide. The curves are drawn 

 through points representing the averages of the individual weights of the rats of 

 litters S8, Sg, and 814, at the various periods. Body weight in grams is repre- 

 sented on the ordinate and age in days on the abscissa. - Controls. 

 - Rats refed after seven weeks of maintenance, 



The rapid growth of the test rats which enabled them to over- 

 take the controls, however, did not persist beyond the point 

 when the normal adult weight was reached. This is evident 

 from the fact that the average adult body weight of the refed 

 animals (Table III.) was not greatly different from that of the 

 controls. Although the controls averaged slightly higher than 

 the test rats of the same sex, the differences are too small to be 

 considered significant. The final weight of the males refed after 

 seven weeks of maintenance averaged considerably below that 



