GROWTH AFTER INANITION FOR VARIOUS PERIODS. 47 



(plus 43.2, 44.5 and 27.9 per cent.) at one, two, and four weeks 

 of refeeding. After four weeks of refeeding (16 weeks of age) 

 the ovaries were practically normal in the controls. In the adult 

 rats the ovaries in both test animals and controls were somewhat 

 below Donaldson's norm. 



It therefore appears that the ovaries on refeeding became 

 heavier than the norm during the earlier periods, reaching a 

 maximum excess weight during the second week, and decreasing 

 to the norm, or below, before the adult stage was reached. 

 How r ever, the large amount of variability in the normal weight 

 of the ovary (due to changes during the sexual cycles) makes any 

 definite conclusions from the available data very difficult or 

 impossible. 



23. Hypophysis (Table V.). 



The weight of the hypophysis at the end of the fasting period 

 was 14.8 per cent, below Donaldson's norm in the male and 9.5 

 per cent, above it in the female. Jackson ('15) noted a distinct 

 tendency for the hypophysis to increase in weight in young 

 rats held at maintenance. 



On refeeding, the hypophysis shows no constant variation 

 from Donaldson's norm. At the end of the fourth week in the 

 test females it was 13.5 per cent, above the norm, whereas the 

 controls were 2.6 per cent, above. The difference is probably 

 due to normal variation and of no special significance. 



In the adult rats the hypophysis weight in both controls and 

 test animals show r s considerable variation from the Wistar norm, 

 being especially high in the females. 



The evidence therefore indicates that the hypophysis was 

 practically normal in weight at all times during the process of 

 refeeding. 



24. Pineal Body (Table V.}. 



On account of lack of data for comparison, no conclusions can 

 be drawn concerning the pineal body in the rats killed at the end 

 of the underfeeding period, and in those refed one half, one, and 

 two weeks. The observations are recorded in Table V. 



In the test rats refed four weeks the gland was apparently 

 normal, the relative weight being .00123 and .00111 per cent. 



