HETEROCHROMOSOMES IN THK GUINEA PIG. 



X. M - 



In \ii-\v of tin- fad lh.it the i:iii' . i- SO much u-ed for 



rimeiiial breedi in Meiidelian heredity. : icd 



di--iraM- i secure some further kno\\le< ; . the behavior ot 



tin- chromatin in ihe ucrm cell-. An attempt ha- t hercf< n\- l>een 

 maili- in folliiw through the -pern, -. and a l>rie! note 



MI t'he -iil.je.-i \\,i^ puhli-hed in tin- BK>I<" i< \i Hi 1.1.1 n\. \'..l. 



XX . \. I. Jaliuarx. I'd I. The material h. <d ti. lie 



\i r\ unfavorable, and the re-ult- an- im: ictorj 



in !M- desired. A- M. ven a \i-r> full actMtmt of 



the transformation of ih -;irrmaiid- int' I -hall 



omit all d ! !u- -pern and 



tiin- IP inion of the rhromatin in tin' 



niirlei and mil- 'erina- 



tid 



MM 



\iin-'' 1 !' fixed b) I uietliod- which had 



material. It 

 idem that onl | -'lemming and Mi rniaiin 



o-n lie mix i ii-. . ! li xation Hi the chromosomes 



ill mi'' -id al-o that th. - nm-t he reino\ed from the 



animal. < lit in!" -mall : red to the fixing fluid 



\\ilh ^reat rapidit\ i' -1 re-uli-. M< 



nu-ihod of n-iiii; ihe lixin^ solul ' pro\ed to In an 



im|>ro\emeni on the !d -olution-. Tin >ns, 5^ 



thick, \\ere -;. lined with I'itlu-r thionin or iron-h.emai"X\ lin, 

 oral g( ( In-ill^ u-ed in >om< a p!a-m.. -I tin. Thionin, 



'hionin and ;lu in. -\ n-ult- 



cia!l> for ihe chroiuo-onie> in niiti \ * aniline prepara- 



tion- \\ere mad' ire-h material and |>ro\cd \alu- 



aMc. h ua- found tha - "! the ti--ti- m. d \\ith 



needle- in carmine would keep in fairly -on.) ccmditioii in 



a ti^lilk -toppered \'ial for several \\eek-. 



