CYTOLOGICAL CHANc.F.S IX EGGS OF RAT. 321 



other two, five eggs contained degenerating r-pimlles while the 

 rest were in an advanced stage of fragmentation. 



Crai k- often appear in the cytoplasm but the zona is >till 

 u-ually intact at this stage. The follicle cells are often grouped 

 into small syncytia containing many small crescent shaped nuclei. 



The eggs of stage three were mostly found in the lower middle 

 portion of the oviduct. In all thirty-six ova were multinucleate. 

 Of these sixteen were unfragmented, and twenty were beginning 

 to fragment. 



Stage IV. I-"ra;.;mentation U-^in- almost simultaneously with 

 K- formation but i- u-ually completed in the most proximal 

 portion of the o\ id in i. Tin- fragments vary in number from two 

 or three to main . Tin \ may b- < >ximately equal in size or 



very tmci|iia!. A fragment may contain one to several nuclei or 

 none. I Lamentation occur- quite independently of the vesi 

 when mai 1 may take place either by a process 



of lobin^. .r. m >re > . ,mnn >nly. by the appearance of cracks in the 

 c\ topla-m. 



- 'me of i he o\ .1 iii i In- IOUIT portion of the oviduct resemble 2, 



nd 4 cell ely. Three two, one three, and 



loin- cell 'iind. In oviduct 32 only one egg in live 



r -mil. led a nonn.,1 condition, the rest being multinucleate and 

 more or less fragmented. In o\iduct 37 two two and one four 

 cell stage \\<i found, while two i-^gs were multinucleate i 

 .mcntcd. Nuinbi-i .ntained very degenerate Ira^mnits 



and one four tdl 1 he c\ topla-m is very degenerate in 



in, -i of ti iirntii'. \ /oiia may or may not be pre-ent 



but if it ap|n-ar- at all it i- nearly always ruptured. The ! 

 meiii- are usually (|iiiie d-\oid of (o\erin- far down in the tube, 

 and it i> ini|>o->ibU- to tell how many ova they come from. The 

 follicle cell- are now empty -hell- devoid of protopla-m. 



romplc-te fragmentation was the rule in nineteen ovidu- 

 All of the-e \\ere found in the lower third of the tube. In all 



twenty-two ova had n 'but this number does not 



repre-ellt the total -ince in -e\'eral ca-es degeneration had pro- 

 , ' eded SO far that the figure- for them had to be omitted. 



