CYTOLOGICAL < EANGES IN" EGGS OF RAT. 323 



spindle and the consequent scattering of the chromosomes 

 throughout the cytoplasm. Kingery ('13) described the same 

 type of degeneration for eggs of the mouse. The cyto- 



plasm and diromosonie- inter that the latter at first appear 



to he surrounded by a lear liquid. They then swell and form 

 little \e-ides resembling nuclei. Where several chromosomes 

 guous lar-e V( -ult. ("harleton ('i/) described 



nueleu- "f tubal mon-' farming from the entire 



chrom- Mp, which th- to a multimicleate cell 



liy l<.linu. Tin- -eriation ht : nU-d demonstrates that this 



in the- r.it. It" 'ins nuclei were 



fu-ing, picture- -ueh a- ( 'harleton ! rihed as due to lobing 



\\< .uld be <.bt. :iiu-d. \\ i M -ribed syncytia in 



artificially p.irt hem i^eiiet i< Poxopneusl _s as resulting from 



.i failure .i" cytokinesis following nuclear di\i-ion by a mitotic 

 proo I ommon a] broken spindles and scat- 



tin in the upper p.irt < .1 the oviduct as well as the 

 different e in ~i/e d" the \ esi( !e~ indi y that this is not 



the case in tub.i! 



\o true multipol.n- -pindle-. inn; or cytasters such 



were de-.-riU-d b> Ht-niii . 5) for atretic rat eggs, by 



Newman i; F the armadillo, and in artificially 



I l-\ Wilson (*oi) were found. 



( )n, in., p pindles at opposite poles of the cell. 



I. ,nn- 'i ; : .nier|ireted .1 -imilar condition in a tubal egg of the 

 -ui hat tl polar body had no: I 



dct. tched from i . but note- that a similar case could not be 



M. inierprete.l -inee the fn>t polar body was clearly present. In 

 \ie\v of t 1 1 i>olar spindle of tubal rat 



r-oi ue time- -n.i|)- in tu I elongation and di-tortion it 



seems best to coii-iiler -uch picture- as originating in thi- manner. 

 1 )uring the MMtterin^; of the chromo-omr- the cytopla-m In-, omes 

 more co.n>ely ^r.inuKir and the nu>he- more opi-n. \\il-on 

 i ibi-d the c\ topla-m of //;/;/; artificially parthenogenetic 

 ser b\- clumpin- of micro-onie- preceding 

 a-ter formation. 



< >nc cell was found with nd one with two re-ling nuclei. 



They are probably the result of chan - of chromi 



