AUTHOR S ABSTRACT OF THIS PAPER ISSUED BY 

 THE BIBLIOGRAPHIC SERVICE, FEBRUARY 28, IQ2I. 



TRANSPLANTATION AND INDIVIDUALITY. 1 



LEO LOEB.2 



INTRODUCTION. 



In this paper I shall report very briefly on a series of experi- 

 ments which have been carried out in our laboratory by ourselves 

 and our associates and in which the method of transplantation 

 was made use of in the analysis of individuality. 



Reactions of tissues serve as indicators with which to judge 

 the interactions of individualities when parts of organisms are 

 transferred into a new soil. Conversely, by means of the re- 

 actions of tissues, which we observe under those conditions, we 

 attempt to obtain an insight into the forces which are active be- 

 tween tissues and into their finer biochemical correlations. Upon 

 these forces depends the preservation of the structure of the 

 organism and thus its maintenance. Thus we hope to contribute 

 to the building up of a physiology of tissue in contradistinction 

 to the physiology of organs. In addition we have studied the lit- 

 erature of transplantation, in order to obtain data which permit 

 the comparison of the interaction of individualities in lower and 

 higher animals and thus to determine whether there are indica- 

 tions that a gradual change has taken place in the course of evo- 

 lution. We shall include in our consideration fertilization which 

 can be considered as an intracellular transplantation. 



Transplantation is the separation of a piece of tissue from its 

 normal surroundings and its transfer into a new environment, 

 either at a new place in the same host ; this we call " autotrans- 

 plantation " ; or into a related individual : " syngenesiotransplan- 

 tation " ; or into a not related individual : " homoiotransplanta- 



1 A lecture delivered at the Marine Biological Laboratory, Woods Hole, 

 on August 3, 1920. A few minor additions to the manuscript have been made 

 subsequently. 



2 From the Department of Comparative Pathology, Washington LJniversity 

 School of Medicine, St. Louis. 



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