52 JACQUES LOEB. 



(Drosophila) in complete darkness without noticing any changes 

 in their eyes or in their sensitiveness to light. 



Recently Uhlenhuth 1 has demonstrated in a very striking 

 way that the development of the eye does not depend upon the 

 influence of the light or upon its functioning. He transplanted 

 the eyes of young salamanders into different parts of their 

 bodies where they were no longer connected with the optic 

 nerves. The eyes after transplantation underwent a degenera- 

 tion which was followed by a complete regeneration. Uhlen- 



BEATING 

 HEART 



FIG. i. 



huth showed that this regeneration took place in complete dark- 

 ness and that in salamanders, kept in the dark for 15 months, 

 the transplanted eyes remained normal. Here the eyes were no 

 longer in connection with the central nervous system, received 

 no light, and could not possibly have functioned and yet they 

 regenerated and kept normal. The degeneration which took 

 place in the eyes immediately after they were transplanted was 



1 Read at the meeting of Anatomists at St. Louis, December 1914. 



