LORANDE LOSS WOODRUFF. 



the methods of conducting the cultures, plotting the graphs, etc., 

 has been fully described in earlier papers from this laboratory, 

 the reader is referred to them for details of technique. It is 

 only necessary to emphasize here that the occurrence of endo- 



FlG. I. 



mixis has been determined, of course, in each case by the cyto- 

 logical study of animals preserved almost daily from each culture 

 during the periods under discussion. 



Race I. (Woodruff's Main Culture.} Isolated May i, 1907, 



at Williamstown, Mass., and carried in pedigreed culture to 



4, 







FIG. 2. 



date (July, 1917). During this period of more than ten years it 

 has attained over 6,000 generations without conjugation. The 

 discovery of endomixis was made on this race and full details 



