108 LEO LOEB. 



grams; examined. Ovaries: Two young corpora lutea with 

 capillaries, with mitoses in lutein and endothelial cells. Atretic 

 yellow bodies. Good small and small-medium follicles; follicles 

 in medium and late connective tissue atresia. Uterus: Epithe- 

 lium in glands high; frequent mitoses in gland fundi. In mucosa 

 predecidual cell layer with frequent mitoses. Mammary gland: 

 Large ducts, acini with rather high cuboidal epithelium, very 

 cellular, not fibrous stroma; probably mitoses in acini. This is 

 an animal at a period about 4^ days after ovulation. Mature 

 follicles developed and ovulation took place. 



Guinea Pig No. f. Hypotypical ovaries of first order with 

 small, vacuolar, retrogressing corpus luteum with thick vessels. 

 Hypotypical uterus with a few mitoses in gland ducts. 



Guinea Pig No. g. Hypotypical ovaries of first order; corpus 

 luteum with vacuolar cells and dense fibrous nucleus; probably 

 15-20 days old. Atretic yellow bodies. Hypotypical uterus. 

 Ovulation had taken place approximately at the time of the 

 beginning of the experiment. The atretic yellow bodies indicate 

 that previous to the experiment the sexual cycle had taken its 

 normal course. 



Guinea Pig No. h. Weight March 24, about 420 grams. 

 April 7, weight 220 grams. April 13, 175 grams. Killed April 

 14. Ovaries: Atretic yellow bodies (remnants of corpora lutea) ; 

 small and small-medium good follicles. In the small-medium 

 follicles atresia sets in and connective tissue grows into the 

 cavity. A few follicles reach almost medium size and then 

 disintegration of the granulosa and connective tissue atresia 

 set in. Only exceptionally a good medium sized follicle present. 

 Hypotypical uterus; some mitoses in surface epithelium. Mam- 

 mary gland: large. Small acini with or without colloid, w r ith 

 low or medium-sized epithelium and partly vacuolar cells. 

 Stroma fibrillar or fibrous. There may have been secretion in 

 this gland previous to the beginning of the experiment. 



Guinea Pig No. i. Hypotypical ovaries of second order with 

 atretic yellow bodies. Hypotypical uterus; some mitoses in 

 surface epithelium. Guinea pigs h and i were evidently not so 

 strongly affected by lack of food. They did not die spon- 

 taneously at the end of the experiment. 



