Relation of Pancreas with Other Endocrine Organs 131 



assists it. It may be that the increased tolerance to sugar which is 

 associated with diminished activity of the thyroid, the posterior lobe of 

 the pituitary, and the medulla of the suprarenals respectively, is brought 

 about through the effect of the changes in those organs upon the pancreas. 



The mode of pi-oduction of pancreatic diabetes is in need of further elucidation. 

 It would appear, however, from what has been above stated, that, apart from the 

 liver, which acts as the main storehouse for carbohydrates, a number of organs 

 are concerned in governing the metabolism and mobilisation of those bodies, all 

 these organs being mutually interdependent. Of such organs the pancreas, pro- 

 bably by virtue of the internal secretion of its islet tissue, may be regarded as 

 occupying the central position. 



The interrelations of these endocrine organs (particularly the thyroid, pancreas, 

 and suprarenals) in connexion with the production of glycaemia and glycosuria 

 have been especially dwelt upon by Eppinger, Falta, and Rudinger. The relations 

 of the internal secretion of the pancreas with glycogenic functions of the liver are 

 dealt with at length by De Meyer, Secretion interne du pancreas, 1910. 



