Effects of Intravenous Injection of Suprarenal Extracts 63 



or of inhibition (intestine (fig. 41), stomach, oesophagus, gall-bladder, urinary 

 bladder). Certain of the plain muscles of the orbit and globe of the eye 

 are excited when suprarenal extract is injected intravenously, so that the 



FIG. 40. Effect of solution of adrenalin on cornu uteri of rabbit, the contraction of which is 

 >* . ^increased. I am indebted to Dr M. Itagaki for the tracings shown in figs. 39 and 40. 



FIG. 41. Effect of immersing a strip of the longitudinal coat of the ileum of a cat in 

 one-in-a-million solution of adrenalin. (A. W. Young.) 



eye tends to protrude and the palpebral fissure becomes large, the third 

 eyelid is retracted and the pupil widely dilated (Lewandowsky). 1 



1 Dropping a solution of adrenalin into the conjunctival sac does not produce dilatation 

 of the pupil unless the superior cervical ganglion of the sympathetic has been previously 

 removed on that side. The removal causes the dilatator pupilla? to be more sensitive to the 

 action of the atitacoid (see p. 60). It is stated by Lb'wi that in diabetes produced by extir- 

 pation of the pancreas, the pupil will react to the instilled solution of adrenalin without 

 such removal of the ganglion. 



