INDEX 



Acetonitrile, resistance to poisonous action in 



mice, 38. 



Acromegaly (see also under Pituitary), 106. 

 causation, 109. 

 symptoms of, 107, 109. 



Addison's disease (see also under Suprarenal), 49. 

 administration of suprarenal extract in, 57. 

 pigmentation in, 49. 

 prognosis of, 49. 



suppression of functions of suprarenal in, 57. 

 symptoms of, 49. 

 Adiposity, relation to pituitary, 101, 102, 111, 



112. 

 relation to sexual organs, 134, 140. 



to thyroid, 31. 



Adrenalin (see also Suprarenal capsules), chem- 

 istry of, 58. 



chromaphil reaction, 50. 

 in diphtheria, 57. 

 disappearance of, in the body, 67. 

 inactivation of, by cerebro-spinal fluid, 67. 



by formaldehyde, 67. 

 medulla of, 58. 



occurrence in skin glands of Bufo, 51. 

 painting pancreas with, 66, 130. 

 passage into blood, 68. 

 physiological effects of, 58. 

 production of hyperglycsemia and glycosuria 



by, 66, 70, 72, 128, 130. 

 relation to melanin, 49. 

 synonyms, 58. 

 synthesis of, 58. 



Adrenals (see Supiarenal capsules). 

 Adrenine (see Adrenalin). 

 Amines, sympatho-mimetic action of, 65. 

 Animal extracts (see also under the various 



organs), 8, 10. 

 Apituitarism, 101, 106. 



Apocodeine, effect on action of adrenalin, 65. 

 Arteries, as test for adrenalin, 62. 

 Atheroma, caused by suprarenal extract, 65. 

 Atropine, effect on action of adrenalin, 59, 71, 



72. 



effect on milk secretion, 94. 

 on pituitary activity, 90. 

 on secretine, 125. 

 Autacoids or autacoid substances (see also under 



the various organs), 6. 

 in blood, 2, 5, 6, 24, 40, 95, 123. 

 classification of, 6. 

 compared with drugs, 6, 8, 90. 

 definition of term, 6. 

 Autotherapy, 10. 



Basedow's disease (see Exophthalmic goitre). 

 Blood, action on adrenalin, 67. 



151 



Blood, adrenalin in, 68. 



autacoids in, 2, 5, 6, 24, 125. 



galactagogue in, 95. 



glycolytic ferment in, 129. 



passage of internal secretions into, 2. 



secretine in, 125. 

 Branchial organs (see Cleft organs). 



Cachexia, hypophyseopriva, 101, 113. 



strumipriva rcl thyreopriva, 32. 

 Calcium metabolism, affected by thyroidectoniy, 



47. 

 in tetany, 26. 



salts, administration in tetany, 26. 

 Cancer cells and internal secretions, 33. 

 Carbohydrate metabolism (see Metabolism, 



carbohydrate). 

 Carotid gland, 51. 

 Castration, effects of, 108, 133. 

 Cells, chromaffine, 51. 



chromaphil, 51. 



internally secreting, 2. 



interstitial, of ovary, 137. 

 of testicle, 132. 



of islets of Langerhans, 126. 



luteal, 138. 



of parathyroid, 17. 



of pineal, 119. 



of pituitary, pars anterior, 79. 

 pars intermedia, 80. 



pregnancy cells, 79. 



of suprarenal cortex, 51. 



of suprarenal medulla, 54. 



of thymus, 46. 



of thyroid, 12. 



Cerebro-spinal fluid, effect on, of extracts of 

 pituitary, 90. 



effect on, of intravenous injection of duodenal 

 extract, 82. 



secretion into, of pars intermedia of pituitary, 



81. 



Chalones, origin and meaning of term, 5. 

 Chalonic autacoids, 6. 

 Chemical messengers, 5. 

 Chromaffine bodies. 51. 



cells, 51. 

 Chromaphil bodies, 51 



development of, 50. 



reaction, 50. 



substance, 58. 

 Cleft organs, 12. 

 Coccygeal gland, 51. 

 Colloid of parathyroid, 20. 



of pituitary, 75. 



of thyroid, 14. 

 Conarium (see Pineal gland). 



