LEO LOEB. 



Ten to eleven days after copulation. The surface epithelium 

 is lower than at the beginning of the sexual cycle; it is cuboiclal 

 or low cylindrical; at certain places there may be swollen cells. 

 There are generally no vacuoles in the epithelium; mitoses are 

 usually missing; they were present only in one place. The glands 

 are small coiled, lying near the surface, are without a wide lumen, 

 their cells are not high and without mitoses. The connective 

 tissue of the mucosa is well supplied with capillaries, which run 

 at right angles to rows of connective tissue cells. The con- 

 nective tissue is still partly myxoid under the surface of the 

 epithelium. At some places there are still many vesicular nuclei 

 densely packed. In the deeper connective tissue between the 

 coils of the glands there are smaller nuclei and some fibrils. 

 Only one mitosis is seen in a connective tissue cell in the mucosa. 

 There is some nuclear debris present under the epithelium ; some 

 mononuclears are in the mucosa tending to migrate through the 

 epithelium. 



Twelve to fourteen days after copulation. Low cuboidal or low 

 cylindrical epithelium of surface with frequent mitoses, especially 

 at places of invagination of the epithelium; glands with low 

 cuboidal or low cylindrical epithelium without mitoses. In the 

 connective tissue there are no mitoses; small vesicular nuclei of 

 connective tissue cells under the epithelium of the surface. The 

 further the connective tissue is removed from the surface epi- 

 thelium, the more the fibrils become developed and the smaller 

 the nuclei. There is occasionally a little edema in the con- 

 nective tissue. Some small mononuclear cells may migrate 

 through the epithelium. The layer of proliferated connective 

 tissue cells which was previously present is much smaller now 

 than five to seven days after ovulation. The glands are cor- 

 respondingly smaller. At this period mitoses appear again in 

 the surface epithelium. 



Fifteen to seventeen days after copulation. The epithelial cells 

 are low cuboidal; mitoses are present only in the surface epi- 

 thelium. The connective tissue contains small nuclei and is 

 fibrillar. Near the surface epithelium the nuclei are relatively 

 more frequent and vesicular in the connective tissue, and the 

 fibrils are less developed than in the deeper parts of the mucosa. 



