12 LEO LOEB. 



Three days after heat we find a vacuolar corpus luteum of the 

 former period, in process of degeneration. In the central cavity 

 of the new corpora lutea new connective tissue is present in the 

 periphery. There are many small, and small to medium-sized 

 good follicles; many follicles in an early-medium stage of con- 

 nective tissue atresia, and a large number of follicles in the late 

 stages of connective tissue atresia. 



The surface epithelium of the uterus is mostly high cylindrical, 

 but may be at places cuboidal, probably as a result of stretching. 

 It does not show any longer the changes observed in the first 

 two days after ovulation. It is usually free from mitoses; the 

 gland duct epithelium is high cylindrical and the epithelium of 

 some fundi begins to become also higher. There are many 

 mitoses present in the gland ducts, especially in their medium 

 parts; the mitoses begin now to proceed further downwards and 

 occasionally may be found in these gland fundi which have 

 enlarged. The connective tissue of the mucosa is, especially in 

 the higher parts, rather cellular, with vesicular nuclei, but without 

 mitoses; it may be somewhat myxoid. 



In the mucosa we find some small mononuclear cells and also 

 s ome polynuclear leucocytes. Some mononuclears may im- 

 migrate into the gland and surface epithelium. There may be 

 seen some cystically dilated glands. 



Four days after heat the corpus luteum of the former period is 

 vacuolar; the new follicles are well developed. There are many 

 small and medium-sized good follicles, and many follicles in 

 medium or the last stage of connective tissue atresia. The 

 epithelium of the surface and gland ducts is no longer as high as 

 before; it is cylindrical, of medium height, or cuboidal-cylin- 

 clrical; the epithelium of the gland fundi is higher than before. 

 There are many mitoses present in the gland fundi ; but nowhere 

 else in the epithelium. Some glands are dilated and contain 

 polynuclear leucocytes. The connective tissue layer under the 

 epithelium is enlarged and shows frequent mitoses. The uterus 

 is slightly papillomatous and in the connective tissue of the 

 papillae there is some edema. The epithelium over the edematous 

 connective tissue may also be edematous. 



Five days after heat, we find in the ovaries many small and 



